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@ARTICLE{Boedhoe:887874,
author = {Boedhoe, Premika S. W. and van Rooij, Daan and Hoogman,
Martine and Twisk, Jos W. R. and Schmaal, Lianne and Abe,
Yoshinari and Alonso, Pino and Ameis, Stephanie H. and
Anikin, Anatoly and Anticevic, Alan and Arango, Celso and
Arnold, Paul D. and Asherson, Philip and Assogna, Francesca
and Auzias, Guillaume and Banaschewski, Tobias and Baranov,
Alexander and Batistuzzo, Marcelo C. and Baumeister, Sarah
and Baur-Streubel, Ramona and Behrmann, Marlene and
Bellgrove, Mark A. and Benedetti, Francesco and Beucke, Jan
C. and Biederman, Joseph and Bollettini, Irene and Bose,
Anushree and Bralten, Janita and Bramati, Ivanei E. and
Brandeis, Daniel and Brem, Silvia and Brennan, Brian P. and
Busatto, Geraldo F. and Calderoni, Sara and Calvo, Anna and
Calvo, Rosa and Castellanos, Francisco X. and Cercignani,
Mara and Chaim-Avancini, Tiffany M. and Chantiluke, Kaylita
C. and Cheng, Yuqi and Cho, Kang Ik K. and Christakou,
Anastasia and Coghill, David and Conzelmann, Annette and
Cubillo, Ana I. and Dale, Anders M. and Dallaspezia, Sara
and Daly, Eileen and Denys, Damiaan and Deruelle, Christine
and Di Martino, Adriana and Dinstein, Ilan and Doyle, Alysa
E. and Durston, Sarah and Earl, Eric A. and Ecker, Christine
and Ehrlich, Stefan and Ely, Benjamin A. and Epstein,
Jeffrey N. and Ethofer, Thomas and Fair, Damien A. and
Fallgatter, Andreas J. and Faraone, Stephen V. and Fedor,
Jennifer and Feng, Xin and Feusner, Jamie D. and Fitzgerald,
Jackie and Fitzgerald, Kate D. and Fouche, Jean-Paul and
Freitag, Christine M. and Fridgeirsson, Egill A. and Frodl,
Thomas and Gabel, Matt C. and Gallagher, Louise and
Gogberashvili, Tinatin and Gori, Ilaria and Gruner, Patricia
and Gürsel, Deniz A. and Haar, Shlomi and Haavik, Jan and
Hall, Geoffrey B. and Harrison, Neil A. and Hartman,
Catharina A. and Heslenfeld, Dirk J. and Hirano, Yoshiyuki
and Hoekstra, Pieter J. and Hoexter, Marcelo Q. and Hohmann,
Sarah and Høvik, Marie F. and Hu, Hao and Huyser, Chaim and
Jahanshad, Neda and Jalbrzikowski, Maria and James, Anthony
and Janssen, Joost and Jaspers-Fayer, Fern and Jernigan,
Terry L. and Kapilushniy, Dmitry and Kardatzki, Bernd and
Karkashadze, Georgii and Kathmann, Norbert and Kaufmann,
Christian and Kelly, Clare and Khadka, Sabin and King,
Joseph A. and Koch, Kathrin and Kohls, Gregor and Konrad,
Kerstin and Kuno, Masaru and Kuntsi, Jonna and Kvale, Gerd
and Kwon, Jun Soo and Lázaro, Luisa and Lera-Miguel, Sara
and Lesch, Klaus-Peter and Hoekstra, Liesbeth and Liu, Yanni
and Lochner, Christine and Louza, Mario R. and Luna, Beatriz
and Lundervold, Astri J. and Malpas, Charles B. and Marques,
Paulo and Marsh, Rachel and Martínez-Zalacaín, Ignacio and
Mataix-Cols, David and Mattos, Paulo and McCarthy, Hazel and
McGrath, Jane and Mehta, Mitul A. and Menchón, José M. and
Mennes, Maarten and Martinho, Mauricio Moller and Moreira,
Pedro S. and Morer, Astrid and Morgado, Pedro and Muratori,
Filippo and Murphy, Clodagh M. and Murphy, Declan G. M. and
Nakagawa, Akiko and Nakamae, Takashi and Nakao, Tomohiro and
Namazova-Baranova, Leyla and Narayanaswamy, Janardhanan C.
and Nicolau, Rosa and Nigg, Joel T. and Novotny, Stephanie
E. and Nurmi, Erika L. and Weiss, Eileen Oberwelland and
O’Gorman Tuura, Ruth L. and O’Hearn, Kirsten and
O’Neill, Joseph and Oosterlaan, Jaap and Oranje, Bob and
Paloyelis, Yannis and Parellada, Mara and Pauli, Paul and
Perriello, Chris and Piacentini, John and Piras, Fabrizio
and Piras, Federica and Plessen, Kerstin J. and Puig, Olga
and Ramos-Quiroga, J. Antoni and Reddy, Y. C. Janardhan and
Reif, Andreas and Reneman, Liesbeth and Retico, Alessandra
and Rosa, Pedro G. P. and Rubia, Katya and Rus, Oana
Georgiana and Sakai, Yuki and Schrantee, Anouk and Schwarz,
Lena and Schweren, Lizanne J. S. and Seitz, Jochen and Shaw,
Philip and Shook, Devon and Silk, Tim J. and Simpson, H.
Blair and Skokauskas, Norbert and Soliva Vila, Juan Carlos
and Solovieva, Anastasia and Soreni, Noam and Soriano-Mas,
Carles and Spalletta, Gianfranco and Stern, Emily R. and
Stevens, Michael C. and Stewart, S. Evelyn and Sudre,
Gustavo and Szeszko, Philip R. and Tamm, Leanne and Taylor,
Margot J. and Tolin, David F. and Tosetti, Michela and
Tovar-Moll, Fernanda and Tsuchiyagaito, Aki and van Erp,
Theo G. M. and van Wingen, Guido A. and Vance, Alasdair and
Venkatasubramanian, Ganesan and Vilarroya, Oscar and
Vives-Gilabert, Yolanda and von Polier, Georg G. and
Walitza, Susanne and Wallace, Gregory L. and Wang, Zhen and
Wolfers, Thomas and Yoncheva, Yuliya N. and Yun, Je-Yeon and
Zanetti, Marcus V. and Zhou, Fengfeng and Ziegler, Georg C.
and Zierhut, Kathrin C. and Zwiers, Marcel P. and Thompson,
Paul M. and Stein, Dan J. and Buitelaar, Jan and Franke,
Barbara and van den Heuvel, Odile A.},
title = {{S}ubcortical {B}rain {V}olume, {R}egional {C}ortical
{T}hickness, and {C}ortical {S}urface {A}rea {A}cross
{D}isorders: {F}indings {F}rom the {ENIGMA} {ADHD}, {ASD},
and {OCD} {W}orking {G}roups},
journal = {The American journal of psychiatry},
volume = {777},
number = {9},
issn = {2474-4662},
address = {[Arlington, VA]},
publisher = {American Psychiatric Association Publishing},
reportid = {FZJ-2020-04496},
pages = {834-843},
year = {2020},
abstract = {Objective: Attention-deficit/hyperactivity disorder (ADHD),
autism spectrum disorder (ASD), andobsessive-compulsive
disorder (OCD) are common neurodevelopmental disorders that
frequently cooccur.We aimed to directly compare all three
disorders. The ENIGMA consortium is ideally positionedto
investigate structural brain differences across these
disorders.Methods: Structural T1-weighted whole-brain MRI of
controls (n=5,827) and patients with ADHD(n=2,271), ASD
(n=1,777), and OCD (n=2,323) from 151 cohorts worldwide were
analyzed usingstandardized processing protocols. We examined
subcortical volume, cortical thickness and surface
areadifferences within a mega-analytical framework, pooling
measures extracted from each cohort.Analyses were performed
separately for children, adolescents, and adults using
linear mixed-effectsmodels adjusting for age, sex and site
(and intra-cranial volume (ICV) for subcortical and surface
areameasures).Results: We found no shared differences among
all three disorders, while shared differences betweenany two
disorders did not survive multiple comparisons correction.
Children with ADHD compared tothose with OCD had smaller
hippocampal volumes, possibly influenced by IQ. Children
andadolescents with ADHD also had smaller ICV than controls
and those with OCD or ASD. Adults withASD showed thicker
frontal cortices compared to adult controls and other
clinical groups. No OCDspecificdifferences across different
age-groups and surface area differences among all disorders
inchildhood and adulthood were observed.},
cin = {INM-7},
ddc = {150},
cid = {I:(DE-Juel1)INM-7-20090406},
pnm = {572 - (Dys-)function and Plasticity (POF3-572)},
pid = {G:(DE-HGF)POF3-572},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:32539527},
UT = {WOS:000564923300012},
doi = {10.1176/appi.ajp.2020.19030331},
url = {https://juser.fz-juelich.de/record/887874},
}