% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Vitusevich:887936,
      author       = {Vitusevich, Svetlana},
      title        = {{C}haracteristic {F}requencies and {T}imes,
                      {S}ignal-to-{N}oise {R}atio and {L}ight {I}llumination
                      {S}tudies in {N}anowire {FET} {B}iosensors : {I}nvited
                      paper},
      journal      = {... IEEE International Symposium on Circuits and Systems
                      proceedings},
      volume       = {9252698},
      issn         = {0271-4302},
      address      = {New York, N.Y.},
      publisher    = {Inst. of Electr. and Electronics Engineers},
      reportid     = {FZJ-2020-04528},
      pages        = {580-585},
      year         = {2020},
      abstract     = {The detection of cardiac biomolecules is of paramount
                      importance for the prospects of fast medical diagnostics of
                      cardiovascular diseases. Silicon nanowire field-effect
                      transistors (NW FETs) are perfect candidates for
                      (bio)sensing studies due to their tremendous sensitivity to
                      changes in surface charge. We present the results of an
                      investigation of transport, fluctuation and modulation
                      phenomena with certain characteristic times in n+-p-n+
                      liquid-gated field-effect transistors (FETs) and compare
                      them with those of p+-p-p+ structures. We reveal the gate
                      coupling effect to be a tool for influencing the channel
                      noise mechanism. n+-p-n+ liquid-gated FETs demonstrate
                      higher signal-to-noise ratios (SNRs) compared to p+-p-p+
                      structures. We show the results of the influence of light
                      waves on the electrical properties of NW FET structures and
                      of studying modulation phenomena in these structures.
                      Excitation of NW samples by light waves allows the effective
                      control of conductance in nanowire channels. Noise spectra
                      and time-dependent modulations of the drain current show
                      promising prospects for enhancing the sensitivity and SNR of
                      nanowire biosensors. The direct translation of periodical
                      signals at a frequency around 1 kHz from the biological
                      object into surface potential changes, caused by interaction
                      with cardiac cells, enables the highly sensitive monitoring
                      of cell dynamic activity before and after pharmacological
                      treatments. Electrical properties of the fabricated Si NW
                      FETs demonstrate high sensitivity for the detection of human
                      C-reactive protein (CRP) – a biomolecule which has
                      recently emerged as a reliable biomarker used in clinical
                      practice for predicting and tracking the state of
                      cardiovascular diseases. The response of the sensor to
                      different concentrations of target CRP molecules, which
                      represent predictable cardio-biomarkers, is studied.
                      Moreover, we reveal that the periodical modulation of drain
                      current due to the single-trap effect may be used to achieve
                      enhanced sensitivity of biosensors. The results are
                      promising for cost-efficient lab-on-chip monitoring, which
                      is especially necessary in the case of acute cardiovascular
                      diseases, where every minute is critical for saving life.},
      month         = {Sep},
      date          = {2020-09-21},
      organization  = {2020 IEEE Ukrainian Microwave Week
                       (UkrMW), Kharkiv (Ukraine), 21 Sep 2020
                       - 25 Sep 2020},
      cin          = {IBI-3},
      ddc          = {620},
      cid          = {I:(DE-Juel1)IBI-3-20200312},
      pnm          = {5241 - Molecular Information Processing in Cellular Systems
                      (POF4-524)},
      pid          = {G:(DE-HGF)POF4-5241},
      typ          = {PUB:(DE-HGF)8 / PUB:(DE-HGF)16},
      doi          = {10.1109/UkrMW49653.2020.9252698},
      url          = {https://juser.fz-juelich.de/record/887936},
}