% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@INPROCEEDINGS{Dabrowska:889317,
      author       = {Dabrowska, Paulina and Voges, Nicole and von Papen, Michael
                      and Ito, Junji and Dahmen, David and Riehle, Alexa and
                      Brochier, Thomas and Grün, Sonja},
      title        = {{C}haracterization of motor cortex spiking activity for
                      spiking neural network model validation},
      reportid     = {FZJ-2021-00209},
      year         = {2020},
      note         = {Since the conference took a virtual format, the posters
                      were presented as 3-min video teasers and live slide
                      presentations (instead of a single-page document).},
      abstract     = {To provide a basis for the validation of balanced spiking
                      neuronal networks and their dynamics, we characterized
                      resting-state (no task) and task-related spiking activity of
                      arm/hand area of macaque (pre-)motor cortex.We recorded
                      spiking activity using a 100-electrode Utah Array (Blackrock
                      Microsystems) during resting-state (REST) and reach-to-grasp
                      (R2G) behavior. In REST, we defined epochs of rest (RS),
                      sleepiness (RSS) and spontaneous movements (M); in R2G:
                      preparatory periods (PP) and task-related movements (TM).
                      Single units were separated into putative excitatory and
                      inhibitory.On the level of single units, we found that
                      $~50\%$ of all units changed their rates significantly with
                      behavioral epochs. Next, we characterized the network
                      activity based on a) the dimensionality which reveals the
                      number of principal components needed to describe the
                      parallel spiking activity, and b) the balance between
                      putative excitatory and inhibitory population firing
                      (absolute difference or instantaneous correlation). RS $\&$
                      PP show the highest dimensionality and the lowest
                      instantaneous balance. Only R2G epochs show a prevalence of
                      excitation (PP) or inhibition (TM), indicating superiority
                      of REST for the validation of balanced network
                      models.Support: DFG SPP1665 DE2175/2-1 $\&$ GR1753/4-2; DFG
                      368482240/GRK2416; EU Grants 720270 $\&$ 785907 (HBP).},
      month         = {Dec},
      date          = {2020-12-08},
      organization  = {NEURONUS 2020 IBRO Neuroscience Forum,
                       virtual (virtual), 8 Dec 2020 - 11 Dec
                       2020},
      subtyp        = {Other},
      cin          = {INM-6 / IAS-6 / INM-10},
      cid          = {I:(DE-Juel1)INM-6-20090406 / I:(DE-Juel1)IAS-6-20130828 /
                      I:(DE-Juel1)INM-10-20170113},
      pnm          = {571 - Connectivity and Activity (POF3-571) / DFG project
                      238707842 - Kausative Mechanismen mesoskopischer
                      Aktivitätsmuster in der auditorischen
                      Kategorien-Diskrimination (238707842) / HBP SGA1 - Human
                      Brain Project Specific Grant Agreement 1 (720270) / HBP SGA2
                      - Human Brain Project Specific Grant Agreement 2 (785907) /
                      PhD no Grant - Doktorand ohne besondere Förderung
                      (PHD-NO-GRANT-20170405)},
      pid          = {G:(DE-HGF)POF3-571 / G:(GEPRIS)238707842 /
                      G:(EU-Grant)720270 / G:(EU-Grant)785907 /
                      G:(DE-Juel1)PHD-NO-GRANT-20170405},
      typ          = {PUB:(DE-HGF)24},
      url          = {https://juser.fz-juelich.de/record/889317},
}