Hauptseite > Publikationsdatenbank > Simultaneous BOLD-fMRI and constant infusion FDG-PET data of the resting human brain > print

001     890228
005     20210208142413.0
024 7 _ |a 10.1038/s41597-020-00699-5
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024 7 _ |a 2052-4436
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100 1 _ |a Jamadar, Sharna D.
|0 0000-0001-7222-7181
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|e Corresponding author
245 _ _ |a Simultaneous BOLD-fMRI and constant infusion FDG-PET data of the resting human brain
260 _ _ |a London
|c 2020
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520 _ _ |a Simultaneous [18 F]-fluorodeoxyglucose positron emission tomography and functional magnetic resonance imaging (FDG-PET/fMRI) provides the capability to image two sources of energetic dynamics in the brain – cerebral glucose uptake and the cerebrovascular haemodynamic response. Resting-state fMRI connectivity has been enormously useful for characterising interactions between distributed brain regions in humans. Metabolic connectivity has recently emerged as a complementary measure to investigate brain network dynamics. Functional PET (fPET) is a new approach for measuring FDG uptake with high temporal resolution and has recently shown promise for assessing the dynamics of neural metabolism. Simultaneous fMRI/fPET is a relatively new hybrid imaging modality, with only a few biomedical imaging research facilities able to acquire FDG PET and BOLD fMRI data simultaneously. We present data for n = 27 healthy young adults (18–20 yrs) who underwent a 95-min simultaneous fMRI/fPET scan while resting with their eyes open. This dataset provides significant re-use value to understand the neural dynamics of glucose metabolism and the haemodynamic response, the synchrony, and interaction between these measures, and the development of new single- and multi-modality image preparation and analysis procedures.
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700 1 _ |a Ward, Phillip G. D.
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700 1 _ |a Close, Thomas G.
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700 1 _ |a Fornito, Alex
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700 1 _ |a Premaratne, Malin
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700 1 _ |a O’Brien, Kieran
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700 1 _ |a Stäb, Daniel
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700 1 _ |a Chen, Zhaolin
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700 1 _ |a Shah, N. J.
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700 1 _ |a Egan, Gary F.
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773 _ _ |a 10.1038/s41597-020-00699-5
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856 4 _ |u https://juser.fz-juelich.de/record/890228/files/s41597-020-00699-5.pdf
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