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@ARTICLE{Papagiannopoulos:890357,
      author       = {Papagiannopoulos, Aristeidis and Pippa, Natassa and
                      Demetzos, Costas and Pispas, Stergios and Radulescu, Aurel},
      title        = {{F}ormation of {U}ni-{L}amellar {V}esicles in {M}ixtures of
                      {DPPC} with {PEO}-b-{PCL} {A}mphiphilic {D}iblock
                      {C}opolymers},
      journal      = {Polymers},
      volume       = {13},
      number       = {1},
      issn         = {2073-4360},
      address      = {Basel},
      publisher    = {MDPI},
      reportid     = {FZJ-2021-00902},
      pages        = {4},
      year         = {2021},
      abstract     = {The ability of mixtures of
                      1.2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and the
                      amphiphilic diblock copolymers poly (ethylene
                      oxide)-block-poly(ε-caprolactone) (PEO-b-PCL) to stabilize
                      uni-lamellar nano-vesicles is reported. Small angle neutron
                      scattering (SANS) is used to define their size distribution
                      and bilayer structure and resolve the copresence of
                      aggregates and clusters in solution. The vesicles have a
                      broad size distribution which is compatible with bilayer
                      membranes of relatively low bending stiffness. Their mean
                      diameter increases moderately with temperature and their
                      number density and mass is higher in the case of the diblock
                      copolymer with the larger hydrophobic block. Bayesian
                      analysis is performed in order to justify the use of the
                      particular SANS fitting model and confirm the reliability of
                      the extracted parameters. This study shows that amphiphilic
                      block copolymers can be effectively used to prepare mixed
                      lipid-block copolymer vesicles with controlled lamellarity
                      and a significant potential as nanocarriers for drug
                      delivery},
      cin          = {JCNS-FRM-II / MLZ / JCNS-1 / JCNS-4},
      ddc          = {540},
      cid          = {I:(DE-Juel1)JCNS-FRM-II-20110218 / I:(DE-588b)4597118-3 /
                      I:(DE-Juel1)JCNS-1-20110106 / I:(DE-Juel1)JCNS-4-20201012},
      pnm          = {6G4 - Jülich Centre for Neutron Research (JCNS) (FZJ)
                      (POF4-6G4)},
      pid          = {G:(DE-HGF)POF4-6G4},
      experiment   = {EXP:(DE-MLZ)KWS2-20140101},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {33375022},
      UT           = {WOS:000606196000001},
      doi          = {10.3390/polym13010004},
      url          = {https://juser.fz-juelich.de/record/890357},
}