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| 001 | 890358 | ||
| 005 | 20240429104852.0 | ||
| 024 | 7 | _ | |a 10.3390/macromol1010004 |2 doi |
| 024 | 7 | _ | |a 2128/28620 |2 Handle |
| 024 | 7 | _ | |a WOS:001204340100001 |2 WOS |
| 037 | _ | _ | |a FZJ-2021-00903 |
| 082 | _ | _ | |a 570 |
| 100 | 1 | _ | |a Papagiannopoulos, Aristeidis |0 P:(DE-HGF)0 |b 0 |e Corresponding author |
| 245 | _ | _ | |a Polyethylene Oxide Hydrogels Crosslinked by Peroxide for the Controlled Release of Proteins |
| 260 | _ | _ | |a Basel |c 2021 |b MDPI AG |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1631517016_15707 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 520 | _ | _ | |a Crosslinking of polyethylene oxide (PEO) using a peroxide in the melt is employed to synthesize soft hydrogels with the ability of controlled release of proteins. The viscoelastic properties of the swollen networks confirm the elastic nature of the synthesized material and they are in agreement with swelling characteristics. The hydrogels have mesh sizes at the nm scale as it is estimated by swelling measurements and measured by small angle neutron scattering (SANS). Diffusion of bovine serum albumin (BSA) and lysozyme (LYZ) out of the hydrogels is restricted by the presence of the network. The diffusion coefficient in the hydrogels is lower for BSA in comparison to LYZ, while in both cases it drops as the mesh size of the network becomes smaller. This study introduces the use of peroxide-crosslinked PEO networks in the investigation of protein transport within hydrogels, the development of hydrogel-based protein delivery patches and polymeric constructs |
| 536 | _ | _ | |a 6G4 - Jülich Centre for Neutron Research (JCNS) (FZJ) (POF4-6G4) |0 G:(DE-HGF)POF4-6G4 |c POF4-6G4 |f POF IV |x 0 |
| 588 | _ | _ | |a Dataset connected to CrossRef |
| 650 | 2 | 7 | |a Soft Condensed Matter |0 V:(DE-MLZ)SciArea-210 |2 V:(DE-HGF) |x 0 |
| 650 | 1 | 7 | |a Polymers, Soft Nano Particles and Proteins |0 V:(DE-MLZ)GC-1602-2016 |2 V:(DE-HGF) |x 0 |
| 693 | _ | _ | |a Forschungs-Neutronenquelle Heinz Maier-Leibnitz |e KWS-2: Small angle scattering diffractometer |f NL3ao |1 EXP:(DE-MLZ)FRMII-20140101 |0 EXP:(DE-MLZ)KWS2-20140101 |5 EXP:(DE-MLZ)KWS2-20140101 |6 EXP:(DE-MLZ)NL3ao-20140101 |x 0 |
| 700 | 1 | _ | |a Vlassi, Eleni |0 P:(DE-HGF)0 |b 1 |e Corresponding author |
| 700 | 1 | _ | |a Pispas, Stergios |0 0000-0002-5347-7430 |b 2 |
| 700 | 1 | _ | |a Tsitsilianis, Constantinos |0 P:(DE-HGF)0 |b 3 |
| 700 | 1 | _ | |a Radulescu, Aurel |0 P:(DE-Juel1)130905 |b 4 |
| 773 | _ | _ | |a 10.3390/macromol1010004 |0 PERI:(DE-600)3091353-6 |n 1 |p 37-48 |t Macromol |v 1 |y 2021 |x 2673-6209 |
| 856 | 4 | _ | |u https://juser.fz-juelich.de/record/890358/files/macromol-01-00004-v2.pdf |y OpenAccess |
| 909 | C | O | |o oai:juser.fz-juelich.de:890358 |p openaire |p open_access |p driver |p VDB:MLZ |p VDB |p dnbdelivery |
| 910 | 1 | _ | |a Forschungszentrum Jülich |0 I:(DE-588b)5008462-8 |k FZJ |b 4 |6 P:(DE-Juel1)130905 |
| 913 | 1 | _ | |a DE-HGF |b Forschungsbereich Materie |l Großgeräte: Materie |1 G:(DE-HGF)POF4-6G0 |0 G:(DE-HGF)POF4-6G4 |3 G:(DE-HGF)POF4 |2 G:(DE-HGF)POF4-600 |4 G:(DE-HGF)POF |v Jülich Centre for Neutron Research (JCNS) (FZJ) |x 0 |
| 913 | 0 | _ | |a DE-HGF |b Forschungsbereich Materie |l Von Materie zu Materialien und Leben |1 G:(DE-HGF)POF3-620 |0 G:(DE-HGF)POF3-623 |3 G:(DE-HGF)POF3 |2 G:(DE-HGF)POF3-600 |4 G:(DE-HGF)POF |v Facility topic: Neutrons for Research on Condensed Matter |9 G:(DE-HGF)POF3-6G4 |x 0 |
| 913 | 0 | _ | |a DE-HGF |b Forschungsbereich Materie |l Großgeräte: Materie |1 G:(DE-HGF)POF3-6G0 |0 G:(DE-HGF)POF3-6G15 |3 G:(DE-HGF)POF3 |2 G:(DE-HGF)POF3-600 |4 G:(DE-HGF)POF |v FRM II / MLZ |x 1 |
| 914 | 1 | _ | |y 2021 |
| 915 | _ | _ | |a OpenAccess |0 StatID:(DE-HGF)0510 |2 StatID |
| 915 | _ | _ | |a Creative Commons Attribution CC BY 4.0 |0 LIC:(DE-HGF)CCBY4 |2 HGFVOC |
| 920 | _ | _ | |l yes |
| 920 | 1 | _ | |0 I:(DE-Juel1)JCNS-FRM-II-20110218 |k JCNS-FRM-II |l JCNS-FRM-II |x 0 |
| 920 | 1 | _ | |0 I:(DE-588b)4597118-3 |k MLZ |l Heinz Maier-Leibnitz Zentrum |x 1 |
| 920 | 1 | _ | |0 I:(DE-Juel1)JCNS-1-20110106 |k JCNS-1 |l Neutronenstreuung |x 2 |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a UNRESTRICTED |
| 980 | _ | _ | |a I:(DE-Juel1)JCNS-FRM-II-20110218 |
| 980 | _ | _ | |a I:(DE-588b)4597118-3 |
| 980 | _ | _ | |a I:(DE-Juel1)JCNS-1-20110106 |
| 980 | 1 | _ | |a FullTexts |
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