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000890460 1001_ $$0P:(DE-HGF)0$$aEschweiler, Mareike$$b0
000890460 245__ $$aCombined cognitive and motor training improves the outcome in the early phase after stroke and prevents a decline of executive functions: A pilot study
000890460 260__ $$aAmsterdam$$bIOS Press$$c2021
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000890460 520__ $$aBACKGROUND:The negative impact of cognitive dysfunction on motor rehabilitation as a relearning-process is well known in stroke patients. However, evidence for combined cognitive and motor training (CMT) is lacking.OBJECTIVE:To evaluate the effects of combined CMT in early stroke rehabilitation.METHODS:In a controlled pilot study, 29 moderately affected stroke patients with low-level motor performance and cognitive impairment received motor therapy plus either cognitive (experimental group, EG) or low-frequency ergometer training (control group, CG) for eight days.RESULTS:Both groups improved their motor functioning significantly. After training, between-group comparison revealed significant differences for cognitive flexibility and trends for set-shifting, working memory, and reaction control in favor of the EG. Within-group effects showed improvement across all cognitive domains in the EG, which correlated with gains in bed-mobility, while the CG showed no significant improvement in cognition. Rather, a trend towards reaction control decline was observed, which correlated with less functional progression and recovery. Furthermore, a decline in cognitive flexibility, set-shifting, and working memory was descriptively observed.CONCLUSIONS:Combined CMT may enhance cognition and motor relearning early after stroke and is superior to single motor training. Further studies are needed to replicate these results and investigate long-term benefits.
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000890460 7001_ $$0P:(DE-HGF)0$$aBohr, Lara$$b1
000890460 7001_ $$0P:(DE-HGF)0$$aKessler, Josef$$b2
000890460 7001_ $$0P:(DE-Juel1)131720$$aFink, Gereon R.$$b3
000890460 7001_ $$0P:(DE-HGF)0$$aKalbe, Elke$$b4$$eCorresponding author
000890460 7001_ $$0P:(DE-HGF)0$$aOnur, Oezguer A.$$b5
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