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@ARTICLE{Eschweiler:890460,
      author       = {Eschweiler, Mareike and Bohr, Lara and Kessler, Josef and
                      Fink, Gereon R. and Kalbe, Elke and Onur, Oezguer A.},
      title        = {{C}ombined cognitive and motor training improves the
                      outcome in the early phase after stroke and prevents a
                      decline of executive functions: {A} pilot study},
      journal      = {Neurorehabilitation},
      volume       = {48},
      number       = {1},
      issn         = {1878-6448},
      address      = {Amsterdam},
      publisher    = {IOS Press},
      reportid     = {FZJ-2021-00974},
      pages        = {97 - 108},
      year         = {2021},
      note         = {Kein Post-print verfügbar!},
      abstract     = {BACKGROUND:The negative impact of cognitive dysfunction on
                      motor rehabilitation as a relearning-process is well known
                      in stroke patients. However, evidence for combined cognitive
                      and motor training (CMT) is lacking.OBJECTIVE:To evaluate
                      the effects of combined CMT in early stroke
                      rehabilitation.METHODS:In a controlled pilot study, 29
                      moderately affected stroke patients with low-level motor
                      performance and cognitive impairment received motor therapy
                      plus either cognitive (experimental group, EG) or
                      low-frequency ergometer training (control group, CG) for
                      eight days.RESULTS:Both groups improved their motor
                      functioning significantly. After training, between-group
                      comparison revealed significant differences for cognitive
                      flexibility and trends for set-shifting, working memory, and
                      reaction control in favor of the EG. Within-group effects
                      showed improvement across all cognitive domains in the EG,
                      which correlated with gains in bed-mobility, while the CG
                      showed no significant improvement in cognition. Rather, a
                      trend towards reaction control decline was observed, which
                      correlated with less functional progression and recovery.
                      Furthermore, a decline in cognitive flexibility,
                      set-shifting, and working memory was descriptively
                      observed.CONCLUSIONS:Combined CMT may enhance cognition and
                      motor relearning early after stroke and is superior to
                      single motor training. Further studies are needed to
                      replicate these results and investigate long-term benefits.},
      cin          = {INM-3},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-3-20090406},
      pnm          = {525 - Decoding Brain Organization and Dysfunction
                      (POF4-525)},
      pid          = {G:(DE-HGF)POF4-525},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {33386825},
      UT           = {WOS:000613235800010},
      doi          = {10.3233/NRE-201583},
      url          = {https://juser.fz-juelich.de/record/890460},
}