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100 1 _ |a Eschweiler, Mareike
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245 _ _ |a Combined cognitive and motor training improves the outcome in the early phase after stroke and prevents a decline of executive functions: A pilot study
260 _ _ |a Amsterdam
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520 _ _ |a BACKGROUND:The negative impact of cognitive dysfunction on motor rehabilitation as a relearning-process is well known in stroke patients. However, evidence for combined cognitive and motor training (CMT) is lacking.OBJECTIVE:To evaluate the effects of combined CMT in early stroke rehabilitation.METHODS:In a controlled pilot study, 29 moderately affected stroke patients with low-level motor performance and cognitive impairment received motor therapy plus either cognitive (experimental group, EG) or low-frequency ergometer training (control group, CG) for eight days.RESULTS:Both groups improved their motor functioning significantly. After training, between-group comparison revealed significant differences for cognitive flexibility and trends for set-shifting, working memory, and reaction control in favor of the EG. Within-group effects showed improvement across all cognitive domains in the EG, which correlated with gains in bed-mobility, while the CG showed no significant improvement in cognition. Rather, a trend towards reaction control decline was observed, which correlated with less functional progression and recovery. Furthermore, a decline in cognitive flexibility, set-shifting, and working memory was descriptively observed.CONCLUSIONS:Combined CMT may enhance cognition and motor relearning early after stroke and is superior to single motor training. Further studies are needed to replicate these results and investigate long-term benefits.
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700 1 _ |a Kessler, Josef
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700 1 _ |a Fink, Gereon R.
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700 1 _ |a Kalbe, Elke
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700 1 _ |a Onur, Oezguer A.
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773 _ _ |a 10.3233/NRE-201583
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