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@ARTICLE{Niu:890495,
author = {Niu, Meiqi and Jankovic-Rapan, Lucija and Funck, Thomas and
Froudist-Walsh, S. and Zhao, Ling and Zilles, Karl and
Palomero-Gallagher, Nicola},
title = {{O}rganization of the {M}acaque {M}onkey {I}nferior
{P}arietal {L}obule {B}ased on {M}ultimodal {R}eceptor
{A}rchitectonics},
journal = {NeuroImage},
volume = {-},
issn = {1053-8119},
address = {Orlando, Fla.},
publisher = {Academic Press},
reportid = {FZJ-2021-00994},
pages = {-},
year = {2021},
abstract = {The macaque monkey inferior parietal lobe (IPL) is a
structurally heterogeneous brain region, although the number
of areas it contains and the anatomical/functional
relationship of identified subdivisions remains
controversial. Neurotransmitter receptor distribution
patterns not only reveal the position of the cortical
borders, but also segregate areas associated to different
functional systems. Thus we carried out a multimodal
quantitative analysis of the cyto- and receptor architecture
of the macaque IPL to determine the number and extent of
distinct areas it encompasses. We identified four areas on
the IPL convexity arranged in a caudo-rostral sequence, as
well as two areas in the parietal operculum, which we
projected onto the Yerkes19 surface. We found rostral areas
to have relatively smaller receptor fingerprints than the
caudal ones, which is in an agreement with the functional
gradient along the caudo-rostral axis described in previous
studies. The hierarchical analysis segregated IPL areas into
two clusters: the caudal one, contains areas involved in
multisensory integration and visual-motor functions, and
rostral cluster, encompasses areas active during motor
planning and action-related functions. The results of the
present study provide novel insights into clarifying the
homologies between human and macaque IPL areas. The ensuing
3D map of the macaque IPL, and the receptor fingerprints are
made publicly available to the neuroscientific community via
the Human Brain Project and BALSA repositories for future
cyto- and/or receptor architectonically driven analyses of
functional imaging studies in non-human primates.},
cin = {INM-1},
ddc = {610},
cid = {I:(DE-Juel1)INM-1-20090406},
pnm = {525 - Decoding Brain Organization and Dysfunction
(POF4-525) / HBP SGA2 - Human Brain Project Specific Grant
Agreement 2 (785907) / HBP SGA3 - Human Brain Project
Specific Grant Agreement 3 (945539) / 3D-MMA -
3D-MMA-Gradienten der Verteilung multipler
Transmitterrezeptoren in der Hirnrinde als Grundlage
verteilter kognitiver, sensorischer und motorischer
Funktionen (BMBF-01GQ1902) / HIBALL - Helmholtz
International BigBrain Analytics and Learning Laboratory
(HIBALL) (InterLabs-0015)},
pid = {G:(DE-HGF)POF4-525 / G:(EU-Grant)785907 /
G:(EU-Grant)945539 / G:(DE-Juel-1)BMBF-01GQ1902 /
G:(DE-HGF)InterLabs-0015},
typ = {PUB:(DE-HGF)16},
pubmed = {33577936},
UT = {WOS:000656561100001},
doi = {10.1016/j.neuroimage.2021.117843},
url = {https://juser.fz-juelich.de/record/890495},
}