TY  - JOUR
AU  - Galldiks, Norbert
AU  - Niyazi, Maximilian
AU  - Grosu, Anca L
AU  - Kocher, Martin
AU  - Langen, Karl-Josef
AU  - Law, Ian
AU  - Minniti, Giuseppe
AU  - Kim, Michelle M
AU  - Tsien, Christina
AU  - Dhermain, Frederic
AU  - Soffietti, Riccardo
AU  - Mehta, Minesh P
AU  - Weller, Michael
AU  - Tonn, Jörg-Christian
TI  - Contribution of PET imaging to radiotherapy planning and monitoring in glioma patients - a report of the PET/RANO group
JO  - Neuro-Oncology
VL  - 23
IS  - 6
SN  - 1523-5866
CY  - Oxford
PB  - Oxford Univ. Press
M1  - FZJ-2021-01076
SP  - 881–893
PY  - 2021
AB  - The management of patients with glioma usually requires multimodality treatment including surgery, radiotherapy, and systemic therapy. Accurate neuroimaging plays a central role for radiotherapy planning and follow-up after radiotherapy completion. In order to maximize the radiation dose to the tumor and to minimize toxic effects on the surrounding brain parenchyma, reliable identification of tumor extent and target volume delineation is crucial. The use of positron emission tomography (PET) for radiotherapy planning and monitoring in gliomas has gained considerable interest over the last several years, but Class I data are not yet available. Furthermore, PET has been used after radiotherapy for response assessment and to distinguish tumor progression from pseudoprogression or radiation necrosis. Here, the Response Assessment in Neuro-Oncology (RANO) working group provides a summary of the literature and recommendations for the use of PET imaging for radiotherapy of patients with glioma based on published studies, constituting levels 1-3 evidence according to the Oxford Centre for Evidence-based Medicine.
LB  - PUB:(DE-HGF)16
C6  - 33538838
UR  - <Go to ISI:>//WOS:000704008200008
DO  - DOI:10.1093/neuonc/noab013
UR  - https://juser.fz-juelich.de/record/890616
ER  -