000890802 001__ 890802
000890802 005__ 20230111074330.0
000890802 0247_ $$2doi$$a10.1186/s13059-020-02158-1
000890802 0247_ $$2ISSN$$a1465-6906
000890802 0247_ $$2ISSN$$a1465-6914
000890802 0247_ $$2ISSN$$a1474-7596
000890802 0247_ $$2ISSN$$a1474-760X
000890802 0247_ $$2Handle$$a2128/27274
000890802 0247_ $$2altmetric$$aaltmetric:90825343
000890802 0247_ $$2pmid$$a32951599
000890802 0247_ $$2WOS$$aWOS:000574470900001
000890802 037__ $$aFZJ-2021-01210
000890802 082__ $$a570
000890802 1001_ $$0P:(DE-HGF)0$$aSchrinner, Sven D.$$b0
000890802 245__ $$aHaplotype threading: accurate polyploid phasing from long reads
000890802 260__ $$aLondon$$bBioMed Central$$c2020
000890802 3367_ $$2DRIVER$$aarticle
000890802 3367_ $$2DataCite$$aOutput Types/Journal article
000890802 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1614610989_8401
000890802 3367_ $$2BibTeX$$aARTICLE
000890802 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000890802 3367_ $$00$$2EndNote$$aJournal Article
000890802 500__ $$aGrant name:de.NBI - Etablierungsphase: Leistungszentrum GCBN – Deutsches BioGreenformatics-Netzwerk für Kulturpflanzen, BMBF 031A536C
000890802 520__ $$aResolving genomes at haplotype level is crucial for understanding the evolutionary history of polyploid species and for designing advanced breeding strategies. Polyploid phasing still presents considerable challenges, especially in regions of collapsing haplotypes.We present WhatsHap polyphase, a novel two-stage approach that addresses these challenges by (i) clustering reads and (ii) threading the haplotypes through the clusters. Our method outperforms the state-of-the-art in terms of phasing quality. Using a real tetraploid potato dataset, we demonstrate how to assemble local genomic regions of interest at the haplotype level. Our algorithm is implemented as part of the widely used open source tool WhatsHap.
000890802 536__ $$0G:(DE-HGF)POF3-899$$a899 - ohne Topic (POF3-899)$$cPOF3-899$$fPOF III$$x0
000890802 588__ $$aDataset connected to CrossRef
000890802 7001_ $$0P:(DE-HGF)0$$aMari, Rebecca Serra$$b1
000890802 7001_ $$0P:(DE-HGF)0$$aEbler, Jana$$b2
000890802 7001_ $$0P:(DE-HGF)0$$aRautiainen, Mikko$$b3
000890802 7001_ $$0P:(DE-HGF)0$$aSeillier, Lancelot$$b4
000890802 7001_ $$0P:(DE-Juel1)185905$$aReimer, Julia J.$$b5
000890802 7001_ $$0P:(DE-Juel1)145719$$aUsadel, Björn$$b6
000890802 7001_ $$0P:(DE-HGF)0$$aMarschall, Tobias$$b7$$eCorresponding author
000890802 7001_ $$00000-0002-6340-0090$$aKlau, Gunnar W.$$b8
000890802 773__ $$0PERI:(DE-600)2040529-7$$a10.1186/s13059-020-02158-1$$gVol. 21, no. 1, p. 252$$n1$$p252$$tGenome biology$$v21$$x1474-760X$$y2020
000890802 8564_ $$uhttps://juser.fz-juelich.de/record/890802/files/s13059-020-02158-1.pdf$$yOpenAccess
000890802 909CO $$ooai:juser.fz-juelich.de:890802$$pdnbdelivery$$pdriver$$pVDB$$popen_access$$popenaire
000890802 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)185905$$aForschungszentrum Jülich$$b5$$kFZJ
000890802 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)145719$$aForschungszentrum Jülich$$b6$$kFZJ
000890802 9101_ $$0I:(DE-HGF)0$$60000-0002-6340-0090$$aExternal Institute$$b8$$kExtern
000890802 9130_ $$0G:(DE-HGF)POF3-899$$1G:(DE-HGF)POF3-890$$2G:(DE-HGF)POF3-800$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bProgrammungebundene Forschung$$lohne Programm$$vohne Topic$$x0
000890802 9131_ $$0G:(DE-HGF)POF4-217$$1G:(DE-HGF)POF4-210$$2G:(DE-HGF)POF4-200$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$9G:(DE-HGF)POF4-2173$$aDE-HGF$$bForschungsbereich Erde und Umwelt$$lErde im Wandel – Unsere Zukunft nachhaltig gestalten$$vFür eine nachhaltige Bio-Ökonomie – von Ressourcen zu Produkten$$x0
000890802 9141_ $$y2021
000890802 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2020-09-08
000890802 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2020-09-08
000890802 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences$$d2020-09-08
000890802 915__ $$0StatID:(DE-HGF)1190$$2StatID$$aDBCoverage$$bBiological Abstracts$$d2020-09-08
000890802 915__ $$0LIC:(DE-HGF)CCBY4$$2HGFVOC$$aCreative Commons Attribution CC BY 4.0
000890802 915__ $$0StatID:(DE-HGF)1040$$2StatID$$aDBCoverage$$bZoological Record$$d2020-09-08
000890802 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bGENOME BIOL : 2018$$d2020-09-08
000890802 915__ $$0StatID:(DE-HGF)9910$$2StatID$$aIF >= 10$$bGENOME BIOL : 2018$$d2020-09-08
000890802 915__ $$0StatID:(DE-HGF)0501$$2StatID$$aDBCoverage$$bDOAJ Seal$$d2020-09-08
000890802 915__ $$0StatID:(DE-HGF)0500$$2StatID$$aDBCoverage$$bDOAJ$$d2020-09-08
000890802 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2020-09-08
000890802 915__ $$0StatID:(DE-HGF)0700$$2StatID$$aFees$$d2020-09-08
000890802 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2020-09-08
000890802 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess
000890802 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bDOAJ : Blind peer review$$d2020-09-08
000890802 915__ $$0StatID:(DE-HGF)0561$$2StatID$$aArticle Processing Charges$$d2020-09-08
000890802 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2020-09-08
000890802 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2020-09-08
000890802 915__ $$0StatID:(DE-HGF)0320$$2StatID$$aDBCoverage$$bPubMed Central$$d2020-09-08
000890802 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2020-09-08
000890802 920__ $$lyes
000890802 9201_ $$0I:(DE-Juel1)IBG-4-20200403$$kIBG-4$$lBioinformatik$$x0
000890802 980__ $$ajournal
000890802 980__ $$aVDB
000890802 980__ $$aUNRESTRICTED
000890802 980__ $$aI:(DE-Juel1)IBG-4-20200403
000890802 9801_ $$aFullTexts