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@ARTICLE{Choi:890895,
      author       = {Choi, Chang-Hoon and Iordanishvili, Elene and Shah, N. J.
                      and Binkofski, Ferdinand},
      title        = {{M}agnetic resonance spectroscopy with transcranial direct
                      current stimulation to explore the underlying biochemical
                      and physiological mechanism of the human brain: {A}
                      systematic review},
      journal      = {Human brain mapping},
      volume       = {42},
      number       = {8},
      issn         = {1097-0193},
      address      = {New York, NY},
      publisher    = {Wiley-Liss},
      reportid     = {FZJ-2021-01226},
      pages        = {2642-2671},
      year         = {2021},
      abstract     = {A large body of molecular and neurophysiological evidence
                      connects synaptic plasticity to specific functions and
                      energy metabolism in particular areas of the brain.
                      Furthermore, altered plasticity and energy regulation has
                      been associated with a number of neuropsychiatric disorders.
                      A favourable approach enabling the modulation of neuronal
                      excitability and energy in humans is to stimulate the brain
                      using transcranial direct current stimulation (tDCS) and
                      then to observe the effect on neurometabolites using
                      magnetic resonance spectroscopy (MRS). In this way, a
                      well‐defined modulation of brain energy and excitability
                      can be achieved using a dedicated tDCS protocol to a
                      predetermined brain region. This systematic review was
                      guided by the preferred reporting items for systematic
                      reviews and meta‐analysis and summarises recent literature
                      studying the effect of tDCS on neurometabolites in the human
                      brain as measured by proton or phosphorus MRS. Limitations
                      and recommendations are discussed for future research. The
                      findings of this review provide clear evidence for the
                      potential of using tDCS and MRS to examine and understand
                      the effect of neurometabolites in the in vivo human brain.},
      cin          = {INM-4 / INM-11 / JARA-BRAIN},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-4-20090406 / I:(DE-Juel1)INM-11-20170113 /
                      I:(DE-Juel1)VDB1046},
      pnm          = {525 - Decoding Brain Organization and Dysfunction
                      (POF4-525)},
      pid          = {G:(DE-HGF)POF4-525},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {33634527},
      UT           = {WOS:000621751000001},
      doi          = {10.1002/hbm.25388},
      url          = {https://juser.fz-juelich.de/record/890895},
}