% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Sarkar:890959,
      author       = {Sarkar, Debarati and Gompper, Gerhard and Elgeti, Jens},
      title        = {{A} minimal model for structure, dynamics, and tension of
                      monolayered cell colonies553},
      journal      = {Communications Physics},
      volume       = {4},
      number       = {1},
      issn         = {2399-3650},
      address      = {London},
      publisher    = {Springer Nature},
      reportid     = {FZJ-2021-01275},
      pages        = {36},
      year         = {2021},
      abstract     = {The motion of cells in tissues is an ubiquitous phenomenon.
                      In particular, in monolayered cell colonies in vitro,
                      pronounced collective behavior with swirl-like motion has
                      been observed deep within a cell colony, while at the same
                      time, the colony remains cohesive, with not a single cell
                      escaping at the edge. Thus, the colony displays liquid-like
                      properties inside, in coexistence with a cell-free
                      “vacuum” outside. We propose an active Brownian particle
                      model with attraction, in which the interaction potential
                      has a broad minimum to give particles enough wiggling space
                      to be collectively in the fluid state. We demonstrate that
                      for moderate propulsion, this model can generate the
                      fluid-vacuum coexistence described above. In addition, the
                      combination of the fluid nature of the colony with cohesion
                      leads to preferred orientation of the cell polarity,
                      pointing outward, at the edge, which in turn gives rise to a
                      tensile stress in the colony—as observed experimentally
                      for epithelial sheets. For stronger propulsion, collective
                      detachment of cell clusters is predicted. Further addition
                      of an alignment preference of cell polarity and velocity
                      direction results in enhanced coordinated, swirl-like
                      motion, increased tensile stress and cell-cluster
                      detachment.},
      cin          = {IBI-5},
      ddc          = {530},
      cid          = {I:(DE-Juel1)IBI-5-20200312},
      pnm          = {524 - Molecular and Cellular Information Processing
                      (POF4-524)},
      pid          = {G:(DE-HGF)POF4-524},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000624638700001},
      doi          = {10.1038/s42005-020-00515-x},
      url          = {https://juser.fz-juelich.de/record/890959},
}