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@ARTICLE{Voelker:891012,
author = {Voelker, Maximilian N. and Kraff, Oliver and Goerke,
Steffen and Laun, Frederik B. and Hanspach, Jannis and Pine,
Kerrin J. and Ehses, Philipp and Zaiss, Moritz and Liebert,
Andrzej and Straub, Sina and Eckstein, Korbinian and
Robinson, Simon and Nagel, Armin N. and Stefanescu, Maria R.
and Wollrab, Astrid and Klix, Sabrina and Felder, Jörg and
Hock, Michael and Bosch, Dario and Weiskopf, Nikolaus and
Speck, Oliver and Ladd, Mark E. and Quick, Harald H.},
title = {{T}he {T}raveling {H}eads 2.0: {M}ulticenter
{R}eproducibility of {Q}uantitative {I}maging {M}ethods at 7
{T}esla},
journal = {NeuroImage},
volume = {232},
issn = {1053-8119},
address = {Orlando, Fla.},
publisher = {Academic Press},
reportid = {FZJ-2021-01308},
pages = {117910 -},
year = {2021},
abstract = {ObjectThis study evaluates inter-site and intra-site
reproducibility at ten different 7 T sites for quantitative
brain imaging.Material and MethodsTwo subjects – termed
the “traveling heads” – were imaged at ten different 7
T sites with a harmonized quantitative brain MR imaging
protocol. In conjunction with the system calibration,
MP2RAGE, QSM, CEST and multi-parametric mapping/relaxometry
were examined.ResultsQuantitative measurements with MP2RAGE
showed very high reproducibility across sites and subjects,
and errors were in concordance with previous results and
other field strengths. QSM had high inter-site
reproducibility for relevant subcortical volumes. CEST
imaging revealed systematic differences between the sites,
but reproducibility was comparable to results in the
literature. Relaxometry had also very high agreement between
sites, but due to the high sensitivity, differences caused
by different applications of the B1 calibration of the two
RF coil types used were observed.ConclusionOur results show
that quantitative brain imaging can be performed with high
reproducibility at 7 T and with similar reliability as found
at 3 T for multicenter studies of the supratentorial brain.},
cin = {INM-4},
ddc = {610},
cid = {I:(DE-Juel1)INM-4-20090406},
pnm = {525 - Decoding Brain Organization and Dysfunction
(POF4-525)},
pid = {G:(DE-HGF)POF4-525},
typ = {PUB:(DE-HGF)16},
pubmed = {33647497},
UT = {WOS:000639114500028},
doi = {10.1016/j.neuroimage.2021.117910},
url = {https://juser.fz-juelich.de/record/891012},
}