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| Hauptseite > Publikationsdatenbank > Magnetic graphene quantum dots facilitate closed-tube one-step detection of SARS-CoV-2 with ultra-low field NMR relaxometry > print |
| Hauptseite > Publikationsdatenbank > Magnetic graphene quantum dots facilitate closed-tube one-step detection of SARS-CoV-2 with ultra-low field NMR relaxometry > print |
| 001 | 891310 | ||
| 005 | 20220103172029.0 | ||
| 024 | 7 | _ | |a 10.1016/j.snb.2021.129786 |2 doi |
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| 100 | 1 | _ | |a Li, Yongqiang |0 0000-0002-3338-1845 |b 0 |
| 245 | _ | _ | |a Magnetic graphene quantum dots facilitate closed-tube one-step detection of SARS-CoV-2 with ultra-low field NMR relaxometry |
| 260 | _ | _ | |a Amsterdam [u.a.] |c 2021 |b Elsevier Science |
| 336 | 7 | _ | |a article |2 DRIVER |
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| 520 | _ | _ | |a The rapid and sensitive diagnosis of the highly contagious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is one of the crucial issues at the outbreak of the ongoing global pandemic that has no valid cure. Here, we propose a SARS-CoV-2 antibody conjugated magnetic graphene quantum dots (GQDs)-based magnetic relaxation switch (MRSw) that specifically recognizes the SARS-CoV-2. The probe of MRSw can be directly mixed with the test sample in a fully sealed vial without sample pretreatment, which largely reduces the testers’ risk of infection during the operation. The closed-tube one-step strategy to detect SARS-CoV-2 is developed with homemade ultra-low field nuclear magnetic resonance (ULF NMR) relaxometry working at 118 μT. The magnetic GQDs-based probe shows ultra-high sensitivity in the detection of SARS-CoV-2 due to its high magnetic relaxivity, and the limit of detection is optimized to 248 Particles mL‒1. Meanwhile, the detection time in ULF NMR system is only 2 min, which can significantly improve the efficiency of detection. In short, the magnetic GQDs-based MRSw coupled with ULF NMR can realize a rapid, safe, and sensitive detection of SARS-CoV-2. |
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| 700 | 1 | _ | |a Yang, Siwei |0 P:(DE-HGF)0 |b 4 |
| 700 | 1 | _ | |a Ding, Guqiao |0 P:(DE-HGF)0 |b 5 |e Corresponding author |
| 700 | 1 | _ | |a Dong, Hui |0 P:(DE-HGF)0 |b 6 |e Corresponding author |
| 700 | 1 | _ | |a Xie, Xiaoming |0 P:(DE-HGF)0 |b 7 |
| 773 | _ | _ | |a 10.1016/j.snb.2021.129786 |g Vol. 337, p. 129786 - |0 PERI:(DE-600)1500731-5 |p 129786 - |t Sensors and actuators |v 337 |y 2021 |x 0925-4005 |
| 856 | 4 | _ | |y Published on 2021-03-15. Available in OpenAccess from 2023-03-15. |z StatID:(DE-HGF)0510 |u https://juser.fz-juelich.de/record/891310/files/Authors%27%20Manuscript%20Final%20Draft%20Post%20Referee.pdf |
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