Hauptseite > Publikationsdatenbank > Quasi-two-dimensional diffusion of interacting globular proteins > print

001     891366
005     20210623133500.0
037 _ _ |a FZJ-2021-01458
041 _ _ |a English
100 1 _ |a Tan, Zihan
|0 P:(DE-Juel1)165875
|b 0
|e Corresponding author
|u fzj
111 2 _ |a APS March Meeting 2021
|c Online
|d 2021-03-15 - 2021-03-19
|w USA
245 _ _ |a Quasi-two-dimensional diffusion of interacting globular proteins
260 _ _ |c 2021
336 7 _ |a Conference Paper
|0 33
|2 EndNote
336 7 _ |a Other
|2 DataCite
336 7 _ |a INPROCEEDINGS
|2 BibTeX
336 7 _ |a conferenceObject
|2 DRIVER
336 7 _ |a LECTURE_SPEECH
|2 ORCID
336 7 _ |a Conference Presentation
|b conf
|m conf
|0 PUB:(DE-HGF)6
|s 1616756869_24004
|2 PUB:(DE-HGF)
|x After Call
500 _ _ |a *Computing time is granted through JARA-HPC on JURECA at the Forschungszentrum Jülich.
520 _ _ |a Diffusion of proteins along lipid membranes plays a vital role in cell signaling processes. How the collective and self-diffusion of proteins are affected by direct and hydrodynamic interactions is relevant, e.g., for protein clustering and oligomerization of receptor protein subunits. Using mesoscale hydrodynamic simulations, the dynamic predictions by a minimalistic protein-membrane-cytosol model are explored. The model describes globular proteins as Brownian spheres, confined to lateral motion in a planar monolayer embedded in a three-dimensional viscous fluid. The proteins are assumed to interact pairwisely either via a hard-core potential or a soft potential consisting of competing short-range attractive and long-range repulsive parts. We analyze spatio-temporal correlations from short times where inertial motion is resolved up to long times where the solvent-mediated hydrodynamic interactions between proteins are fully developed. In this context, we investigate the short-time buildup of inter-protein hydrodynamic interactions by multiple scattering of sound and vorticity diffusion, and long-time anomalous enhancement of collective diffusion, in their dependence on protein concentration.
536 _ _ |a 524 - Molecular and Cellular Information Processing (POF4-524)
|0 G:(DE-HGF)POF4-524
|c POF4-524
|x 0
|f POF IV
700 1 _ |a Dhont, Jan K.G.
|0 P:(DE-Juel1)130616
|b 1
|u fzj
700 1 _ |a Calandrini, Vania
|0 P:(DE-Juel1)166168
|b 2
|u fzj
700 1 _ |a Naegele, Gerhard
|0 P:(DE-Juel1)130858
|b 3
|e Corresponding author
|u fzj
856 4 _ |u https://meetings.aps.org/Meeting/MAR21/Session/C16.2
909 C O |o oai:juser.fz-juelich.de:891366
|p VDB
910 1 _ |a Forschungszentrum Jülich
|0 I:(DE-588b)5008462-8
|k FZJ
|b 0
|6 P:(DE-Juel1)165875
910 1 _ |a Forschungszentrum Jülich
|0 I:(DE-588b)5008462-8
|k FZJ
|b 1
|6 P:(DE-Juel1)130616
910 1 _ |a Forschungszentrum Jülich
|0 I:(DE-588b)5008462-8
|k FZJ
|b 2
|6 P:(DE-Juel1)166168
910 1 _ |a Forschungszentrum Jülich
|0 I:(DE-588b)5008462-8
|k FZJ
|b 3
|6 P:(DE-Juel1)130858
913 0 _ |a DE-HGF
|b Key Technologies
|l BioSoft – Fundamentals for future Technologies in the fields of Soft Matter and Life Sciences
|1 G:(DE-HGF)POF3-550
|0 G:(DE-HGF)POF3-551
|3 G:(DE-HGF)POF3
|2 G:(DE-HGF)POF3-500
|4 G:(DE-HGF)POF
|v Functional Macromolecules and Complexes
|x 0
913 1 _ |a DE-HGF
|b Key Technologies
|l Natural, Artificial and Cognitive Information Processing
|1 G:(DE-HGF)POF4-520
|0 G:(DE-HGF)POF4-524
|3 G:(DE-HGF)POF4
|2 G:(DE-HGF)POF4-500
|4 G:(DE-HGF)POF
|v Molecular and Cellular Information Processing
|x 0
914 1 _ |y 2021
920 _ _ |l yes
920 1 _ |0 I:(DE-Juel1)IBI-4-20200312
|k IBI-4
|l Biomakromolekulare Systeme und Prozesse
|x 0
980 _ _ |a conf
980 _ _ |a VDB
980 _ _ |a I:(DE-Juel1)IBI-4-20200312
980 _ _ |a UNRESTRICTED

LibraryCollectionCLSMajorCLSMinorLanguageAuthor
Marc 21