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| Hauptseite > Publikationsdatenbank > Quasi-two-dimensional diffusion of interacting globular proteins > print |
| Hauptseite > Publikationsdatenbank > Quasi-two-dimensional diffusion of interacting globular proteins > print |
| 001 | 891367 | ||
| 005 | 20210623133359.0 | ||
| 037 | _ | _ | |a FZJ-2021-01459 |
| 041 | _ | _ | |a English |
| 100 | 1 | _ | |a Tan, Zihan |0 P:(DE-Juel1)165875 |b 0 |e Corresponding author |u fzj |
| 111 | 2 | _ | |a IBI-4 Group seminar |c Jülich |d 2021-03-09 - 2021-03-09 |w Germany |
| 245 | _ | _ | |a Quasi-two-dimensional diffusion of interacting globular proteins |f 2021-03-09 - |
| 260 | _ | _ | |c 2021 |
| 336 | 7 | _ | |a Conference Paper |0 33 |2 EndNote |
| 336 | 7 | _ | |a Other |2 DataCite |
| 336 | 7 | _ | |a INPROCEEDINGS |2 BibTeX |
| 336 | 7 | _ | |a LECTURE_SPEECH |2 ORCID |
| 336 | 7 | _ | |a Talk (non-conference) |b talk |m talk |0 PUB:(DE-HGF)31 |s 1616686675_5562 |2 PUB:(DE-HGF) |x Other |
| 336 | 7 | _ | |a Other |2 DINI |
| 500 | _ | _ | |a *Computing time is granted through JARA-HPC on JURECA at the Forschungszentrum Jülich. |
| 520 | _ | _ | |a Diffusion of proteins along lipid membranes plays a vital role in cell signaling processes. How the collective and self-diffusion of proteins are affected by direct and hydrodynamic interactions is relevant, e.g., for protein clustering and oligomerization of receptor protein subunits. Using mesoscale hydrodynamic simulations, the dynamic predictions by a minimalistic protein-membrane-cytosol model are explored. The model describes globular proteins as Brownian spheres, confined to lateral motion in a planar monolayer embedded in a three-dimensional viscous fluid. The proteins are assumed to interact pairwisely either via a hard-core potential or a soft potential consisting of competing short-range attractive and long-range repulsive parts. We analyze spatio-temporal correlations from short times where inertial motion is resolved up to long times where the solvent-mediated hydrodynamic interactions between proteins are fully developed. In this context, we investigate the short-time buildup of inter-protein hydrodynamic interactions by multiple scattering of sound and vorticity diffusion, and long-time anomalous enhancement of collective diffusion, in their dependence on protein concentration. |
| 536 | _ | _ | |a 524 - Molecular and Cellular Information Processing (POF4-524) |0 G:(DE-HGF)POF4-524 |c POF4-524 |x 0 |f POF IV |
| 909 | C | O | |o oai:juser.fz-juelich.de:891367 |p VDB |
| 910 | 1 | _ | |a Forschungszentrum Jülich |0 I:(DE-588b)5008462-8 |k FZJ |b 0 |6 P:(DE-Juel1)165875 |
| 913 | 0 | _ | |a DE-HGF |b Key Technologies |l BioSoft – Fundamentals for future Technologies in the fields of Soft Matter and Life Sciences |1 G:(DE-HGF)POF3-550 |0 G:(DE-HGF)POF3-551 |3 G:(DE-HGF)POF3 |2 G:(DE-HGF)POF3-500 |4 G:(DE-HGF)POF |v Functional Macromolecules and Complexes |x 0 |
| 913 | 1 | _ | |a DE-HGF |b Key Technologies |l Natural, Artificial and Cognitive Information Processing |1 G:(DE-HGF)POF4-520 |0 G:(DE-HGF)POF4-524 |3 G:(DE-HGF)POF4 |2 G:(DE-HGF)POF4-500 |4 G:(DE-HGF)POF |v Molecular and Cellular Information Processing |x 0 |
| 914 | 1 | _ | |y 2021 |
| 920 | _ | _ | |l yes |
| 920 | 1 | _ | |0 I:(DE-Juel1)IBI-4-20200312 |k IBI-4 |l Biomakromolekulare Systeme und Prozesse |x 0 |
| 980 | _ | _ | |a talk |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a I:(DE-Juel1)IBI-4-20200312 |
| 980 | _ | _ | |a UNRESTRICTED |
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