TY - JOUR AU - Tahmasian, Masoud AU - Aleman, André AU - Andreassen, Ole A. AU - Arab, Zahra AU - Baillet, Marion AU - Benedetti, Francesco AU - Bresser, Tom AU - Bright, Joanna AU - Chee, Michael W. L. AU - Chylinski, Daphné AU - Cheng, Wei AU - Deantoni, Michele AU - Dresler, Martin AU - Eickhoff, Simon B. AU - Eickhoff, Claudia R. AU - Elvsåshagen, Torbjørn AU - Feng, Jianfeng AU - Foster-Dingley, Jessica C. AU - Ganjgahi, Habib AU - Grabe, Hans J. AU - Groenewold, Nynke A. AU - Ho, Tiffani C. AU - Hong, Seung Bong AU - Houenou, Josselin AU - Irungu, Benson AU - Jahanshad, Neda AU - Khazaie, Habibolah AU - Kim, Hosung AU - Koshmanova, Ekaterina AU - Kocevska, Desi AU - Kochunov, Peter AU - Lakbila-Kamal, Oti AU - Leerssen, Jeanne AU - Li, Meng AU - Luik, Annemarie I. AU - Muto, Vincenzo AU - Narbutas, Justinas AU - Nilsonne, Gustav AU - O’Callaghan, Victoria S. AU - Olsen, Alexander AU - Osorio Suarez, Ricardo M. AU - Poletti, Sara AU - Poudel, Govinda AU - Reesen, Joyce E. AU - Reneman, Liesbeth AU - Reyt, Mathilde AU - Riemann, Dieter AU - Rosenzweig, Ivana AU - Rostampour, Masoumeh AU - Saberi, Amin AU - Schiel, Julian AU - Schmidt, Christina AU - Schrantee, Anouk AU - Sciberras, Emma AU - Silk, Tim J. AU - Sim, Kang AU - Smevik, Hanne AU - Soares, Jair C. AU - Spiegelhalder, Kai AU - Stein, Dan J. AU - Talwar, Puneet AU - Tamm, Sandra AU - Teresi, Giana l. AU - Valk, Sofie L. AU - Someren, Eus van AU - Vandewalle, Gilles AU - Egroo, Maxime Van AU - Völzke, Henry AU - Walter, Martin AU - Wassing, Rick AU - Weber, Frederik D. AU - Weihs, Antoine AU - Westlye, Lars Tjelta AU - Wright, Margaret J. AU - Wu, Mon-Ju AU - Zak, Nathalia AU - Zarei, Mojtaba TI - ENIGMA-Sleep: challenges, opportunities, and the road map JO - Journal of sleep research VL - 30 IS - 6 SN - 0962-1105 CY - Oxford [u.a.] PB - Wiley-Blackwell M1 - FZJ-2021-01673 SP - e13347 PY - 2021 AB - Neuroimaging and genetics studies have advanced our understanding of the neurobiology of sleep and its disorders. However, individual studies usually have limitations to identifying consistent and reproducible effects, including modest sample sizes, heterogeneous clinical characteristics, and varied methodologies. These issues call for a large-scale multi-center effort in sleep research, in order to increase the number of samples, and harmonize the methods of data collection, preprocessing, and analysis using pre-registered well-established protocols. The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) consortium provides a powerful collaborative framework for combining datasets across individual sites. Recently, we have launched the ENIGMA-Sleep working group with the collaboration of several institutes from 15 countries to perform large-scale worldwide neuroimaging and genetics studies for better understanding on the neurobiology of impaired sleep quality in population-based healthy individuals, the neural consequences of sleep deprivation, pathophysiology of sleep disorders, as well as neural correlates of sleep disturbances across various neuropsychiatric disorders. In this introductory review, we describe the details of our currently available datasets and our ongoing projects in the ENIGMA-Sleep group, and discuss both the potential challenges and opportunities of a collaborative initiative in sleep medicine. LB - PUB:(DE-HGF)16 C6 - pmid:33913199 UR - <Go to ISI:>//WOS:000645057500001 DO - DOI:10.1111/jsr.13347 UR - https://juser.fz-juelich.de/record/891692 ER -