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@ARTICLE{Lindemeyer:892715,
      author       = {Lindemeyer, Johannes and Worthoff, Wieland A. and
                      Shymanskaya, Aliaksandra and Shah, N. Jon},
      title        = {{I}terative {R}estoration of the {F}ringe {P}hase
                      ({REFRASE}) for {QSM}},
      journal      = {Frontiers in neuroscience},
      volume       = {15},
      issn         = {1662-453X},
      address      = {Lausanne},
      publisher    = {Frontiers Research Foundation},
      reportid     = {FZJ-2021-02285},
      pages        = {537666},
      year         = {2021},
      abstract     = {In quantitative susceptibility mapping (QSM), reconstructed
                      results can be critically biased by misinterpreted or
                      missing phase data near the edges of the brain support
                      originating from the non-local relationship between field
                      and susceptibility. These data either have to be excluded or
                      corrected before further processing can take place. To
                      address this, our iterative restoration of the fringe phase
                      (REFRASE) approach simultaneously enhances the accuracy of
                      multi-echo phase data QSM maps and the extent of the area
                      available for evaluation. Data loss caused by strong local
                      phase gradients near the surface of the brain support is
                      recovered within the original phase data using harmonic and
                      dipole-based fields extrapolated from a robust support
                      region toward an extended brain mask. Over several
                      iterations, phase data are rectified prior to the
                      application of further QSM processing steps. The concept is
                      successfully validated on numerical phantoms and brain scans
                      from a cohort of volunteers. The increased extent of the
                      mask and improved numerical stability within the segmented
                      globus pallidus confirm the efficacy of the presented method
                      in comparison to traditional evaluation.},
      cin          = {INM-4 / INM-11 / JARA-BRAIN},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-4-20090406 / I:(DE-Juel1)INM-11-20170113 /
                      I:(DE-Juel1)VDB1046},
      pnm          = {525 - Decoding Brain Organization and Dysfunction
                      (POF4-525)},
      pid          = {G:(DE-HGF)POF4-525},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {34054401},
      UT           = {WOS:000654971500001},
      doi          = {10.3389/fnins.2021.537666},
      url          = {https://juser.fz-juelich.de/record/892715},
}