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@ARTICLE{Popovych:892819,
author = {Popovych, Oleksandr V. and Jung, Kyesam and Manos, Thanos
and Diaz-Pier, Sandra and Hoffstaedter, Felix and Schreiber,
Jan and Yeo, B. T. Thomas and Eickhoff, Simon B.},
title = {{I}nter-subject and inter-parcellation variability of
resting-state whole-brain dynamical modeling},
journal = {NeuroImage},
volume = {236},
issn = {1053-8119},
address = {Orlando, Fla.},
publisher = {Academic Press},
reportid = {FZJ-2021-02365},
pages = {118201 -},
year = {2021},
abstract = {Modern approaches to investigate complex brain dynamics
suggest to represent the brain as a functional network of
brain regions defined by a brain atlas, while edges
represent the structural or functional connectivity among
them. This approach is also utilized for mathematical
modeling of the resting-state brain dynamics, where the
applied brain parcellation plays an essential role in
deriving the model network and governing the modeling
results. There is however no consensus and empirical
evidence on how a given brain atlas affects the model
outcome, and the choice of parcellation is still rather
arbitrary. Accordingly, we explore the impact of brain
parcellation on inter-subject and inter-parcellation
variability of model fitting to empirical data. Our
objective is to provide a comprehensive empirical evidence
of potential influences of parcellation choice on
resting-state whole-brain dynamical modeling. We show that
brain atlases strongly influence the quality of model
validation and propose several variables calculated from
empirical data to account for the observed variability. A
few classes of such data variables can be distinguished
depending on their inter-subject and inter-parcellation
explanatory power.},
cin = {INM-7},
ddc = {610},
cid = {I:(DE-Juel1)INM-7-20090406},
pnm = {5232 - Computational Principles (POF4-523) / 5231 -
Neuroscientific Foundations (POF4-523) / SLNS - SimLab
Neuroscience (Helmholtz-SLNS)},
pid = {G:(DE-HGF)POF4-5232 / G:(DE-HGF)POF4-5231 /
G:(DE-Juel1)Helmholtz-SLNS},
typ = {PUB:(DE-HGF)16},
pubmed = {34033913},
UT = {WOS:000670278100013},
doi = {10.1016/j.neuroimage.2021.118201},
url = {https://juser.fz-juelich.de/record/892819},
}