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@INPROCEEDINGS{Wiegand:892894,
      author       = {Wiegand, Simone},
      title        = {{T}hermophoresis of biological and biocompatible compounds
                      in aqueous solution},
      reportid     = {FZJ-2021-02421},
      year         = {2021},
      abstract     = {With rising popularity of Microscale Thermophoresis for the
                      characterisation of protein-ligand binding reactions and
                      possible applications in microfluidic devices, there is a
                      growing interest in considering thermodiffusion in the
                      context of life sciences. But although the understanding of
                      thermodiffusion in non-polar mixtures has grown rapidly in
                      recent years, predictions for associated mixtures like
                      aqueous solutions remain challenging. This talk aims to give
                      an overview of the literature on thermodiffusion in aqueous
                      systems, show the difficulties in theoretical description
                      that arise from the non-ideal behaviour of water-mixtures,
                      and highlight the relevance of thermodiffusion in a
                      biological context. We find that the thermodiffusion in
                      aqueous systems is dominated by contributions from heat of
                      transfer, hydrogen bond interactions and charge effects.
                      However, the separation of these effects is often difficult,
                      especially in case of biological systems where a systematic
                      exclusion of contributions may not be feasible. Beside the
                      deficiencies of the theoretical analysis, we will also
                      elucidate the shortcomings of the available experimental
                      methods handling the biological multicomponent systems.
                      References Niether, D.; Wiegand, S., J. Phys. Condens.
                      Matter, 31 (2019) 503003:1-25.},
      month         = {May},
      date          = {2021-05-25},
      organization  = {14th International Meeting on
                       Thermodiffusion, Norway (virtuell)
                       (Norway), 25 May 2021 - 27 May 2021},
      subtyp        = {Invited},
      cin          = {IBI-4},
      cid          = {I:(DE-Juel1)IBI-4-20200312},
      pnm          = {524 - Molecular and Cellular Information Processing
                      (POF4-524)},
      pid          = {G:(DE-HGF)POF4-524},
      typ          = {PUB:(DE-HGF)6},
      url          = {https://juser.fz-juelich.de/record/892894},
}