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037 _ _ |a FZJ-2021-02421
041 _ _ |a English
100 1 _ |a Wiegand, Simone
|0 P:(DE-Juel1)131034
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|e Corresponding author
|u fzj
111 2 _ |a 14th International Meeting on Thermodiffusion
|g IMT 14
|c Norway (virtuell)
|d 2021-05-25 - 2021-05-27
|w Norway
245 _ _ |a Thermophoresis of biological and biocompatible compounds in aqueous solution
260 _ _ |c 2021
336 7 _ |a Conference Paper
|0 33
|2 EndNote
336 7 _ |a Other
|2 DataCite
336 7 _ |a INPROCEEDINGS
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336 7 _ |a conferenceObject
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336 7 _ |a LECTURE_SPEECH
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336 7 _ |a Conference Presentation
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|x Invited
520 _ _ |a With rising popularity of Microscale Thermophoresis for the characterisation of protein-ligand binding reactions and possible applications in microfluidic devices, there is a growing interest in considering thermodiffusion in the context of life sciences. But although the understanding of thermodiffusion in non-polar mixtures has grown rapidly in recent years, predictions for associated mixtures like aqueous solutions remain challenging. This talk aims to give an overview of the literature on thermodiffusion in aqueous systems, show the difficulties in theoretical description that arise from the non-ideal behaviour of water-mixtures, and highlight the relevance of thermodiffusion in a biological context. We find that the thermodiffusion in aqueous systems is dominated by contributions from heat of transfer, hydrogen bond interactions and charge effects. However, the separation of these effects is often difficult, especially in case of biological systems where a systematic exclusion of contributions may not be feasible. Beside the deficiencies of the theoretical analysis, we will also elucidate the shortcomings of the available experimental methods handling the biological multicomponent systems. References Niether, D.; Wiegand, S., J. Phys. Condens. Matter, 31 (2019) 503003:1-25.
536 _ _ |a 524 - Molecular and Cellular Information Processing (POF4-524)
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909 C O |o oai:juser.fz-juelich.de:892894
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910 1 _ |a Forschungszentrum Jülich
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|b Key Technologies
|l BioSoft – Fundamentals for future Technologies in the fields of Soft Matter and Life Sciences
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|v Functional Macromolecules and Complexes
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914 1 _ |y 2021
920 _ _ |l yes
920 1 _ |0 I:(DE-Juel1)IBI-4-20200312
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|l Biomakromolekulare Systeme und Prozesse
|x 0
980 _ _ |a conf
980 _ _ |a VDB
980 _ _ |a I:(DE-Juel1)IBI-4-20200312
980 _ _ |a UNRESTRICTED


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