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@ARTICLE{Liang:893110,
author = {Liang, Yuanying and Offenhäusser, Andreas and Ingebrandt,
Sven and Mayer, Dirk},
title = {{PEDOT}:{PSS}‐{B}ased {B}ioelectronic {D}evices for
{R}ecording and {M}odulation of {E}lectrophysiological and
{B}iochemical {C}ell {S}ignals},
journal = {Advanced healthcare materials},
volume = {10},
number = {11},
issn = {2192-2659},
address = {Weinheim},
publisher = {Wiley-VCH},
reportid = {FZJ-2021-02568},
pages = {2100061},
year = {2021},
abstract = {To understand the physiology and pathology of electrogenic
cells and the corresponding tissue in their full complexity,
the quantitative investigation of the transmission of ions
as well as the release of chemical signals is important.
Organic (semi-) conducting materials and in particular
organic electrochemical transistor are gaining in importance
for the investigation of electrophysiological and recently
biochemical signals due to their synthetic nature and thus
chemical diversity and modifiability, their biocompatible
and compliant properties, as well as their mixed electronic
and ionic conductivity featuring ion-to-electron conversion.
Here, the aim is to summarize recent progress on the
development of bioelectronic devices utilizing polymer
polyethylenedioxythiophene: poly(styrene sulfonate)
(PEDOT:PSS) to interface electronics and biological matter
including microelectrode arrays, neural cuff electrodes,
organic electrochemical transistors, PEDOT:PSS-based
biosensors, and organic electronic ion pumps. Finally,
progress in the material development is summarized for the
improvement of polymer conductivity, stretchability, higher
transistor transconductance, or to extend their field of
application such as cation sensing or metabolite
recognition. This survey of recent trends in PEDOT:PSS
electrophysiological sensors highlights the potential of
this multifunctional material to revolve current technology
and to enable long-lasting, multichannel polymer probes for
simultaneous recordings of electrophysiological and
biochemical signals from electrogenic cells.},
cin = {IBI-3},
ddc = {610},
cid = {I:(DE-Juel1)IBI-3-20200312},
pnm = {5244 - Information Processing in Neuronal Networks
(POF4-524)},
pid = {G:(DE-HGF)POF4-5244},
typ = {PUB:(DE-HGF)16},
pubmed = {33970552},
UT = {WOS:000648612900001},
doi = {10.1002/adhm.202100061},
url = {https://juser.fz-juelich.de/record/893110},
}