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@ARTICLE{AlfonsoPrieto:893381,
      author       = {Alfonso-Prieto, Mercedes},
      title        = {{B}itter {T}aste and {O}lfactory {R}eceptors: {B}eyond
                      {C}hemical {S}ensing in the {T}ongue and the {N}ose},
      journal      = {The journal of membrane biology},
      volume       = {254},
      number       = {4},
      issn         = {1432-1424},
      address      = {Heidelberg},
      publisher    = {Springer},
      reportid     = {FZJ-2021-02722},
      pages        = {343-352},
      year         = {2021},
      note         = {Open Access publication; funding enabled and organized by
                      Projekt DEAL.},
      abstract     = {The Up-and-Coming-Scientist section of the current issue of
                      the Journal of Membrane Biology features the invited essay
                      by Dr. Mercedes Alfonso-Prieto, Assistant Professor at the
                      Forschungszentrum Jülich (FZJ), Germany, and the
                      Heinrich-Heine University Düsseldorf, Vogt Institute for
                      Brain Research. Dr. Alfonso-Prieto completed her doctoral
                      degree in chemistry at the Barcelona Science Park, Spain, in
                      2009, pursued post-doctoral research in computational
                      molecular sciences at Temple University, USA, and then, as a
                      Marie Curie post-doctoral fellow at the University of
                      Barcelona, worked on computations of enzyme reactions and
                      modeling of photoswitchable ligands targeting neuronal
                      receptors. In 2016, she joined the Institute for Advanced
                      Science and the Institute for Computational Biomedicine at
                      the FZJ, where she pursues research on modeling and
                      simulation of chemical senses. The invited essay by Dr.
                      Alfonso-Prieto discusses state-of-the-art modeling of
                      molecular receptors involved in chemical sensing – the
                      senses of taste and smell. These receptors, and
                      computational methods to study them, are the focus of Dr.
                      Alfonso-Prieto’s research. Recently, Dr. Alfonso-Prieto
                      and colleagues have presented a new methodology to predict
                      ligand binding poses for GPCRs, and extensive computations
                      that deciphered the ligand selectivity determinants of
                      bitter taste receptors. These developments inform our
                      current understanding of how taste occurs at the molecular
                      level.},
      cin          = {IAS-5 / INM-9},
      ddc          = {570},
      cid          = {I:(DE-Juel1)IAS-5-20120330 / I:(DE-Juel1)INM-9-20140121},
      pnm          = {5241 - Molecular Information Processing in Cellular Systems
                      (POF4-524) / 5251 - Multilevel Brain Organization and
                      Variability (POF4-525)},
      pid          = {G:(DE-HGF)POF4-5241 / G:(DE-HGF)POF4-5251},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {34173018},
      UT           = {WOS:000667454400001},
      doi          = {10.1007/s00232-021-00182-1},
      url          = {https://juser.fz-juelich.de/record/893381},
}