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000894461 1001_ $$0P:(DE-HGF)0$$aWolf, Sabrina$$b0
000894461 245__ $$aAdvances in metabolic engineering of Corynebacterium glutamicum to produce high-value active ingredients for food, feed, human health, and well-being
000894461 260__ $$aLondon$$bPortland Press$$c2021
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000894461 500__ $$aBiotechnologie 1
000894461 520__ $$aThe soil microbe Corynebacterium glutamicum is a leading workhorse in industrial biotechnology and has become famous for its power to synthetise amino acids and a range of bulk chemicals at high titre and yield. The product portfolio of the microbe is continuously expanding. Moreover, metabolically engineered strains of C. glutamicum produce more than 30 high value active ingredients, including signature molecules of raspberry, savoury, and orange flavours, sun blockers, anti-ageing sugars, and polymers for regenerative medicine. Herein, we highlight recent advances in engineering of the microbe into novel cell factories that overproduce these precious molecules from pioneering proofs-of-concept up to industrial productivity.
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000894461 7001_ $$0P:(DE-HGF)0$$aBecker, Judith$$b1
000894461 7001_ $$0P:(DE-HGF)0$$aTsuge, Yota$$b2
000894461 7001_ $$0P:(DE-HGF)0$$aKawaguchi, Hideo$$b3
000894461 7001_ $$0P:(DE-HGF)0$$aKondo, Akihiko$$b4
000894461 7001_ $$0P:(DE-Juel1)144031$$aMarienhagen, Jan$$b5
000894461 7001_ $$0P:(DE-Juel1)128943$$aBott, Michael$$b6
000894461 7001_ $$0P:(DE-HGF)0$$aWendisch, Volker F.$$b7
000894461 7001_ $$0P:(DE-HGF)0$$aWittmann, Christoph$$b8$$eCorresponding author
000894461 773__ $$0PERI:(DE-600)2242123-3$$a10.1042/EBC20200134$$gVol. 65, no. 2, p. 197 - 212$$n2$$p197 - 212$$tEssays in biochemistry$$v65$$x1744-1358$$y2021
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