TY  - JOUR
AU  - Habel, U.
AU  - Koch, K.
AU  - Kellermann, T.
AU  - Reske, M.
AU  - Frommann, N.
AU  - Wölwer, W.
AU  - Zilles, K.
AU  - Shah, J. N.
AU  - Schneider, F.
TI  - Training of affect recognition in schizophrenia: Neurobiological correlates
JO  - Social neuroscience
VL  - 5
SN  - 1747-0919
CY  - New York [u.a.]
PB  - Psychology Press
M1  - PreJuSER-8980
SP  - 92 - 104
PY  - 2010
N1  - This work was supported by the German Research Foundation DFG, Schn 362/13-1 and 13-2, KFO 112/2-1 and 2-2, the Research Center Julich, the Federal Ministry of Education and Research (German Research Network on Schizophrenia 01 GI 9932).
AB  - Recently, a standardized program for training of affect recognition (TAR) was developed which has demonstrated efficacy and specificity with respect to behavioral performance. The effects of the TAR on the cerebral correlates were evaluated using repeated fMRI event-related measurements in a group of schizophrenia patients (n=10) before and after TAR treatment six weeks apart. A second patient group without training (n=10, treatment as usual, TAU) as well as healthy subjects (n=10) were investigated at equivalent time points. Schizophrenia patients were shown to be differentially impaired in the identification of the emotional aspects of facial expressions (but not age discrimination) when compared with healthy participants. A specific improvement in the increased number of correct identifications was observed in trained patients only. In parallel, an increase in activation was noted in the left middle and superior occipital lobe, the right inferior and superior parietal cortex, and the inferior frontal cortex bilaterally in TAR patients compared to the TAU group. These activation changes in TAR patients correlated with their behavioral improvement, further corroborating the positive effect of training. Specific training effects are seen to correspond with cerebral effects, probably reflecting a more efficient use of attentional, perceptual, or cognitive strategies.
KW  - Adult
KW  - Analysis of Variance
KW  - Brain Mapping
KW  - Cerebral Cortex: blood supply
KW  - Cerebral Cortex: pathology
KW  - Discrimination (Psychology): physiology
KW  - Emotions: physiology
KW  - Functional Laterality: physiology
KW  - Humans
KW  - Image Processing, Computer-Assisted: methods
KW  - Magnetic Resonance Imaging: methods
KW  - Male
KW  - Neuropsychological Tests
KW  - Oxygen: blood
KW  - Reaction Time: physiology
KW  - Recognition (Psychology): physiology
KW  - Regression Analysis
KW  - Schizophrenia: rehabilitation
KW  - Schizophrenic Psychology
KW  - Severity of Illness Index
KW  - Teaching: methods
KW  - Young Adult
KW  - Oxygen (NLM Chemicals)
KW  - J (WoSType)
LB  - PUB:(DE-HGF)16
C6  - pmid:19821187
UR  - <Go to ISI:>//WOS:000277748800007
DO  - DOI:10.1080/17470910903170269
UR  - https://juser.fz-juelich.de/record/8980
ER  -