TY  - JOUR
AU  - Wojciechowski, Kamil
AU  - Jurek, Ilona
AU  - Góral, Ilona
AU  - Campana, Mario
AU  - Geue, Thomas
AU  - Gutberlet, Thomas
TI  - Surface-active extracts from plants rich in saponins – effect on lipid mono- and bilayers
JO  - Surfaces and Interfaces
VL  - 27
SN  - 2468-0230
CY  - Amsterdam
PB  - Elsevier
M1  - FZJ-2021-04001
SP  - 101486 -
PY  - 2021
AB  - The aqueous extracts of the seeds of oat (Avena sativa L.), horse chestnut (Aesculus hippocastanum L.), soybean (Glycine max L.), cowherb (Vaccaria hispanica [P. Mill.] Rauschert) and quinoa (Chenopodium quinoa Willd.), and the roots of soapwort (Saponaria officinalis L.) without any preservatives were characterized in terms of theirsurface tension, surface compression (dilational) rheology, foamability and foam stability. The saponin content in the extracts was determined using UPLC-MS and their interaction with model lipid monolayers consisting of dipalmitoylphosphatidylcholine (DPPC)/cholesterol and Ceramide AP/stearic acid/cholesterol were analyzed by surface pressure relaxation, surface compression elasticity and neutron reflectometry (NR). The lipid composition was chosen to mimic the cell membrane of keratinocytes – major constituents of the human deeper skin layers, and the intercellular lipids (“mortar”) in the “bricks and mortar” model of the outermost layer of the epidermis (stratum corneum). Bilayers of DPPC/cholesterol were additionally characterized using dynamic light scattering (DLS) and NR. The oat and soybean extracts were shown to be much less abundant in saponins as compared to cowherb, horse chestnut, soapwort or quinoa, and showed limited foaming abilities. They did not affect significantly the model lipid mono- and bilayers mimicking the skin outer layers, either. The horse chestnut extract affected both model membranes to the highest extent, yet without solubilizing the lipids.
LB  - PUB:(DE-HGF)16
UR  - <Go to ISI:>//WOS:000711758500003
DO  - DOI:10.1016/j.surfin.2021.101486
UR  - https://juser.fz-juelich.de/record/902053
ER  -