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000902213 1001_ $$0P:(DE-HGF)0$$aSchweitzer, Finja$$b0
000902213 245__ $$aCerebrospinal Fluid Analysis Post–COVID-19 Is Not Suggestive of Persistent Central Nervous System Infection
000902213 260__ $$aHoboken, NJ$$bWiley-Blackwell$$c2022
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000902213 520__ $$aThis study was undertaken to assess whether SARS-CoV-2 causes a persistent central nervous system infection. SARS-CoV-2–specific antibody index and SARS-CoV-2 RNA were studied in cerebrospinal fluid following COVID-19. Cerebrospinal fluid was assessed between days 1 and 30 (n = 12), between days 31 and 90 (n = 8), or later than 90 days (post–COVID-19, n = 20) after COVID-19 diagnosis. SARS-CoV-2 RNA was absent in all patients, and in none of the 20 patients with post–COVID-19 syndrome were intrathecally produced anti–SARS-CoV-2 antibodies detected. The absence of evidence of SARS-CoV-2 in cerebrospinal fluid argues against a persistent central nervous system infection as a cause of neurological or neuropsychiatric post–COVID-19 syndrome. ANN NEUROL 2022;91:150–157
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000902213 7001_ $$0P:(DE-HGF)0$$aGoereci, Yasemin$$b1
000902213 7001_ $$00000-0002-5609-2472$$aFranke, Christiana$$b2
000902213 7001_ $$0P:(DE-HGF)0$$aSilling, Steffi$$b3
000902213 7001_ $$0P:(DE-HGF)0$$aBösl, Fabian$$b4
000902213 7001_ $$0P:(DE-HGF)0$$aMaier, Franziska$$b5
000902213 7001_ $$0P:(DE-HGF)0$$aHeger, Eva$$b6
000902213 7001_ $$0P:(DE-HGF)0$$aDeiman, Birgit$$b7
000902213 7001_ $$00000-0002-8283-7976$$aPrüss, Harald$$b8
000902213 7001_ $$0P:(DE-HGF)0$$aOnur, Oezguer A.$$b9
000902213 7001_ $$0P:(DE-HGF)0$$aKlein, Florian$$b10
000902213 7001_ $$0P:(DE-Juel1)131720$$aFink, Gereon Rudolf$$b11$$ufzj
000902213 7001_ $$0P:(DE-HGF)0$$aDi Cristanziano, Veronica$$b12
000902213 7001_ $$00000-0002-3510-9255$$aWarnke, Clemens$$b13$$eCorresponding author
000902213 773__ $$0PERI:(DE-600)2037912-2$$a10.1002/ana.26262$$gp. ana.26262$$n1$$p150-157$$tAnnals of neurology$$v91$$x1531-8249$$y2022
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