%0 Journal Article
%A Genon, Sarah
%A Bernhardt, Boris C.
%A La Joie, Renaud
%A Amunts, Katrin
%A Eickhoff, Simon B.
%T The many dimensions of human hippocampal organization and (dys)function
%J Trends in neurosciences
%V 44
%N 12
%@ 0166-2236
%C Amsterdam [u.a.]
%I Elsevier Science
%M FZJ-2021-04363
%P 977-989
%D 2021
%X Magnetic resonance imaging–based parcellation of the hippocampal formation and gradient mapping are data-driven techniques that can capture many dimensions of hippocampal organization and provide readily usable outcomes.    Features of cortical architecture, such as local connectivity and microstructure, reveal differentiation within the hippocampal formation along the medial–lateral axis. This organizational dimension seemingly reflects local information-processing organization.    Neuroimaging markers tapping into hippocampal integration into large-scale networks (i.e., whole-brain connectivity) highlight the long-axis differentiation.    The long-axis organization corresponds to a molecular gradient and differential integration across distinct behavioral systems.    Capitalizing on gradients and parcellations maps, the long-axis organization of the hippocampal formation can be related to behavioral phenotypes in healthy and clinical populations.
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:34756460
%U <Go to ISI:>//WOS:000722893100008
%R 10.1016/j.tins.2021.10.003
%U https://juser.fz-juelich.de/record/902564