TY  - JOUR
AU  - Genon, Sarah
AU  - Bernhardt, Boris C.
AU  - La Joie, Renaud
AU  - Amunts, Katrin
AU  - Eickhoff, Simon B.
TI  - The many dimensions of human hippocampal organization and (dys)function
JO  - Trends in neurosciences
VL  - 44
IS  - 12
SN  - 0166-2236
CY  - Amsterdam [u.a.]
PB  - Elsevier Science
M1  - FZJ-2021-04363
SP  - 977-989
PY  - 2021
AB  - Magnetic resonance imaging–based parcellation of the hippocampal formation and gradient mapping are data-driven techniques that can capture many dimensions of hippocampal organization and provide readily usable outcomes.    Features of cortical architecture, such as local connectivity and microstructure, reveal differentiation within the hippocampal formation along the medial–lateral axis. This organizational dimension seemingly reflects local information-processing organization.    Neuroimaging markers tapping into hippocampal integration into large-scale networks (i.e., whole-brain connectivity) highlight the long-axis differentiation.    The long-axis organization corresponds to a molecular gradient and differential integration across distinct behavioral systems.    Capitalizing on gradients and parcellations maps, the long-axis organization of the hippocampal formation can be related to behavioral phenotypes in healthy and clinical populations.
LB  - PUB:(DE-HGF)16
C6  - pmid:34756460
UR  - <Go to ISI:>//WOS:000722893100008
DO  - DOI:10.1016/j.tins.2021.10.003
UR  - https://juser.fz-juelich.de/record/902564
ER  -