%0 Journal Article
%A Bauer, Elena Katharina
%A Werner, Jan-Michael
%A Fink, Gereon R.
%A Langen, Karl-Josef
%A Galldiks, Norbert
%T Case Report: Detection of Symptomatic Treatment-Related Changes in a Patient With Anaplastic Oligodendroglioma Using FET PET
%J Frontiers in oncology
%V 11
%@ 2234-943X
%C Lausanne
%I Frontiers Media
%M FZJ-2021-04913
%P 735388
%D 2021
%X Following local and systemic treatment of gliomas, the differentiation between glioma relapse and treatment-related changes such as pseudoprogression or radiation necrosis using conventional MRI is limited. To overcome this limitation, various amino acid PET tracers such as O-[2-(18F)-fluoroethyl]-L-tyrosine (FET) are increasingly used and provide valuable additional clinical information. We here report neuroimaging findings in a clincally symptomatic 53-year-old woman with a recurrent anaplastic oligodendroglioma with MRI findings highly suspicious for tumor progression. In contrast, FET PET imaging suggested treatment-related changes considerably earlier than the regression of contrast enhancement on MRI. In patients with oligodendroglioma, the phenomenon of symptomatic treatment-related changes is not well described, making these imaging findings unique and important for clinical decision-making.
%F PUB:(DE-HGF)16
%9 Journal Article
%$ 34868923
%U <Go to ISI:>//WOS:000726120200001
%R 10.3389/fonc.2021.735388
%U https://juser.fz-juelich.de/record/903194