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000903194 1001_ $$0P:(DE-HGF)0$$aBauer, Elena Katharina$$b0
000903194 245__ $$aCase Report: Detection of Symptomatic Treatment-Related Changes in a Patient With Anaplastic Oligodendroglioma Using FET PET
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000903194 520__ $$aFollowing local and systemic treatment of gliomas, the differentiation between glioma relapse and treatment-related changes such as pseudoprogression or radiation necrosis using conventional MRI is limited. To overcome this limitation, various amino acid PET tracers such as O-[2-(18F)-fluoroethyl]-L-tyrosine (FET) are increasingly used and provide valuable additional clinical information. We here report neuroimaging findings in a clincally symptomatic 53-year-old woman with a recurrent anaplastic oligodendroglioma with MRI findings highly suspicious for tumor progression. In contrast, FET PET imaging suggested treatment-related changes considerably earlier than the regression of contrast enhancement on MRI. In patients with oligodendroglioma, the phenomenon of symptomatic treatment-related changes is not well described, making these imaging findings unique and important for clinical decision-making.
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000903194 7001_ $$0P:(DE-HGF)0$$aWerner, Jan-Michael$$b1
000903194 7001_ $$0P:(DE-Juel1)131720$$aFink, Gereon R.$$b2$$ufzj
000903194 7001_ $$0P:(DE-Juel1)131777$$aLangen, Karl-Josef$$b3$$ufzj
000903194 7001_ $$0P:(DE-Juel1)143792$$aGalldiks, Norbert$$b4$$eCorresponding author$$ufzj
000903194 773__ $$0PERI:(DE-600)2649216-7$$a10.3389/fonc.2021.735388$$gVol. 11, p. 735388$$p735388$$tFrontiers in oncology$$v11$$x2234-943X$$y2021
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