TY  - JOUR
AU  - Bauer, Elena Katharina
AU  - Werner, Jan-Michael
AU  - Fink, Gereon R.
AU  - Langen, Karl-Josef
AU  - Galldiks, Norbert
TI  - Case Report: Detection of Symptomatic Treatment-Related Changes in a Patient With Anaplastic Oligodendroglioma Using FET PET
JO  - Frontiers in oncology
VL  - 11
SN  - 2234-943X
CY  - Lausanne
PB  - Frontiers Media
M1  - FZJ-2021-04913
SP  - 735388
PY  - 2021
AB  - Following local and systemic treatment of gliomas, the differentiation between glioma relapse and treatment-related changes such as pseudoprogression or radiation necrosis using conventional MRI is limited. To overcome this limitation, various amino acid PET tracers such as O-[2-(18F)-fluoroethyl]-L-tyrosine (FET) are increasingly used and provide valuable additional clinical information. We here report neuroimaging findings in a clincally symptomatic 53-year-old woman with a recurrent anaplastic oligodendroglioma with MRI findings highly suspicious for tumor progression. In contrast, FET PET imaging suggested treatment-related changes considerably earlier than the regression of contrast enhancement on MRI. In patients with oligodendroglioma, the phenomenon of symptomatic treatment-related changes is not well described, making these imaging findings unique and important for clinical decision-making.
LB  - PUB:(DE-HGF)16
C6  - 34868923
UR  - <Go to ISI:>//WOS:000726120200001
DO  - DOI:10.3389/fonc.2021.735388
UR  - https://juser.fz-juelich.de/record/903194
ER  -