Home > Publications database > Case Report: Detection of Symptomatic Treatment-Related Changes in a Patient With Anaplastic Oligodendroglioma Using FET PET > print

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024 7 _ |a 10.3389/fonc.2021.735388
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100 1 _ |a Bauer, Elena Katharina
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245 _ _ |a Case Report: Detection of Symptomatic Treatment-Related Changes in a Patient With Anaplastic Oligodendroglioma Using FET PET
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520 _ _ |a Following local and systemic treatment of gliomas, the differentiation between glioma relapse and treatment-related changes such as pseudoprogression or radiation necrosis using conventional MRI is limited. To overcome this limitation, various amino acid PET tracers such as O-[2-(18F)-fluoroethyl]-L-tyrosine (FET) are increasingly used and provide valuable additional clinical information. We here report neuroimaging findings in a clincally symptomatic 53-year-old woman with a recurrent anaplastic oligodendroglioma with MRI findings highly suspicious for tumor progression. In contrast, FET PET imaging suggested treatment-related changes considerably earlier than the regression of contrast enhancement on MRI. In patients with oligodendroglioma, the phenomenon of symptomatic treatment-related changes is not well described, making these imaging findings unique and important for clinical decision-making.
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700 1 _ |a Werner, Jan-Michael
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700 1 _ |a Fink, Gereon R.
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700 1 _ |a Langen, Karl-Josef
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700 1 _ |a Galldiks, Norbert
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773 _ _ |a 10.3389/fonc.2021.735388
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856 4 _ |u https://juser.fz-juelich.de/record/903194/files/fonc-11-735388.pdf
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