TY  - JOUR
AU  - De Sousa, A.A.
AU  - Sherwood, C.C.
AU  - Schleicher, A.
AU  - Amunts, K.
AU  - MacLeod, C.E.
AU  - Hof, P.R.
AU  - Zilles, K.
TI  - Comparative Cytoarchitectural Analyses of Striate and Extrastriate Areas in Hominoids
JO  - Cerebral cortex
VL  - 20
SN  - 1047-3211
CY  - Oxford
PB  - Oxford Univ. Press
M1  - PreJuSER-9035
SP  - 966 - 987
PY  - 2010
N1  - National Science Foundation (9987590, 01-113); the James S. McDonnell Foundation (22002078).
AB  - The visual cortex is the largest sensory modality representation in the neocortex of humans and closely related species, and its size and organization has a central role in discussions of brain evolution. Yet little is known about the organization of visual brain structures in the species closest to humans--the apes--thus, making it difficult to evaluate hypotheses about recent evolutionary changes. The primate visual cortex is comprised of numerous cytoarchitectonically distinct areas, each of which has a specific role in the processing of visual stimuli. We examined the histological organization of striate (V1) and 2 extrastriate (V2 and ventral posterior) cortical areas in humans, 5 ape species, and a macaque. The cytoarchitectural patterns of visual areas were compared across species using quantitative descriptions of cell volume densities and laminar patterns. We also investigated potential scaling relationships between cell volume density and several brain, body, and visual system variables. The results suggest that interspecific variability in the cytoarchitectural organization of visual system structures can arise independently of global brain and body size scaling relationships. In particular, species-specific differences in cell volume density seem to be most closely linked to the size of structures in the visual system.
KW  - Animals
KW  - Biological Evolution
KW  - Brain Mapping
KW  - Cell Count
KW  - Cell Size
KW  - Hominidae: anatomy & histology
KW  - Hominidae: classification
KW  - Humans
KW  - Neurons: physiology
KW  - Species Specificity
KW  - Visual Cortex: cytology
KW  - Visual Fields
KW  - Visual Pathways
KW  - J (WoSType)
LB  - PUB:(DE-HGF)16
C6  - pmid:19776344
UR  - <Go to ISI:>//WOS:000275566500018
DO  - DOI:10.1093/cercor/bhp158
UR  - https://juser.fz-juelich.de/record/9035
ER  -