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@ARTICLE{Gertig:904186,
author = {Gertig, Christoph and Fleitmann, Lorenz and Hemprich, Carl
and Hense, Janik and Bardow, André and Leonhard, Kai},
title = {{CAT}-{COSMO}-{CAMPD}: {I}ntegrated in silico design of
catalysts and processes based on quantum chemistry},
journal = {Computers $\&$ chemical engineering},
volume = {153},
issn = {0098-1354},
address = {Amsterdam [u.a.]},
publisher = {Elsevier Science},
reportid = {FZJ-2021-05756},
pages = {107438 -},
year = {2021},
abstract = {Catalysts are of paramount importance as most chemical
processes would be uneconomical without suitable catalysts.
Consequently, the identification of appropriate catalysts is
a key step in chemical process design. However, the number
of potential catalysts is usually vast. To suggest promising
candidates for experimental testing, in silico catalyst
design methods are highly desirable. Still, such
computational methods are in their infancy. Moreover, simple
performance indicators are commonly employed as design
objective instead of evaluating the actual process
performance enabled by considered catalysts. Here, we
present the CAT-COSMO-CAMPD method for integrated in silico
design of homogeneous molecular catalysts and processes.
CAT-COSMO-CAMPD integrates design of molecular catalysts
with process optimization, enabling a process-based
evaluation of every designed candidate catalyst. Reaction
kinetics of catalytic reactions are predicted by advanced
quantum chemical methods. We demonstrate for a catalytic
carbamate-cleavage process that CAT-COSMO-CAMPD successfully
identifies catalyst molecules maximizing the predicted
process performance.},
cin = {IEK-10},
ddc = {660},
cid = {I:(DE-Juel1)IEK-10-20170217},
pnm = {899 - ohne Topic (POF4-899)},
pid = {G:(DE-HGF)POF4-899},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000684566700008},
doi = {10.1016/j.compchemeng.2021.107438},
url = {https://juser.fz-juelich.de/record/904186},
}