%0 Journal Article
%A Weissbecker, Juliane
%A Boumrifak, Chokri
%A Breyer, Maximilian
%A Wießalla, Tristan
%A Shevchenko, Vitaly
%A Mager, Thomas
%A Slavov, Chavdar
%A Alekseev, Alexey
%A Kovalev, Kirill
%A Gordeliy, Valentin
%A Bamberg, Ernst
%A Wachtveitl, Josef
%T The Voltage Dependent Sidedness of the Reprotonation of the Retinal Schiff Base Determines the Unique Inward Pumping of Xenorhodopsin
%J Angewandte Chemie / International edition
%V 60
%N 42
%@ 0570-0833
%C Weinheim
%I Wiley-VCH
%M FZJ-2021-05888
%P 23010 - 23017
%D 2021
%X The unique behaviour of inward proton pumping xenorhodopsins (XeR) makes these microbial rhodopsins an alternative optogenetic tool to the passively transporting light-gated ion channels (e.g. channelrhodopsin-1 and channelrhodopsin-2), because the activation of electrically excitable cells by XeRs is independent from the surrounding physiological conditions. Here, we functionally and spectroscopically characterized XeR from Nanosalina (NsXeR)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:34339559
%U <Go to ISI:>//WOS:000695899000001
%R 10.1002/anie.202103882
%U https://juser.fz-juelich.de/record/904318