TY - JOUR
AU - Weissbecker, Juliane
AU - Boumrifak, Chokri
AU - Breyer, Maximilian
AU - Wießalla, Tristan
AU - Shevchenko, Vitaly
AU - Mager, Thomas
AU - Slavov, Chavdar
AU - Alekseev, Alexey
AU - Kovalev, Kirill
AU - Gordeliy, Valentin
AU - Bamberg, Ernst
AU - Wachtveitl, Josef
TI - The Voltage Dependent Sidedness of the Reprotonation of the Retinal Schiff Base Determines the Unique Inward Pumping of Xenorhodopsin
JO - Angewandte Chemie / International edition
VL - 60
IS - 42
SN - 0570-0833
CY - Weinheim
PB - Wiley-VCH
M1 - FZJ-2021-05888
SP - 23010 - 23017
PY - 2021
AB - The unique behaviour of inward proton pumping xenorhodopsins (XeR) makes these microbial rhodopsins an alternative optogenetic tool to the passively transporting light-gated ion channels (e.g. channelrhodopsin-1 and channelrhodopsin-2), because the activation of electrically excitable cells by XeRs is independent from the surrounding physiological conditions. Here, we functionally and spectroscopically characterized XeR from Nanosalina (NsXeR)
LB - PUB:(DE-HGF)16
C6 - pmid:34339559
UR - <Go to ISI:>//WOS:000695899000001
DO - DOI:10.1002/anie.202103882
UR - https://juser.fz-juelich.de/record/904318
ER -