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@ARTICLE{Jablonski:904350,
author = {Jablonski, Melanie and Poghossian, Arshak and Severins,
Robin and Keusgen, Michael and Wege, Christina and
Schöning, Michael J.},
title = {{C}apacitive {F}ield-{E}ffect {B}iosensor {S}tudying
{A}dsorption of {T}obacco {M}osaic {V}irus {P}articles},
journal = {Micromachines},
volume = {12},
number = {1},
issn = {2072-666X},
address = {Basel},
publisher = {MDPI},
reportid = {FZJ-2021-05920},
pages = {57 -},
year = {2021},
abstract = {Plant virus-like particles, and in particular, tobacco
mosaic virus (TMV) particles, are increasingly being used in
nano- and biotechnology as well as for biochemical sensing
purposes as nanoscaffolds for the high-density
immobilization of receptor molecules. The sensitive
parameters of TMV-assisted biosensors depend, among others,
on the density of adsorbed TMV particles on the sensor
surface, which is affected by both the adsorption conditions
and surface properties of the sensor. In this work,
Ta2O5-gate field-effect capacitive sensors have been applied
for the label-free electrical detection of TMV adsorption.
The impact of the TMV concentration on both the sensor
signal and the density of TMV particles adsorbed onto the
Ta2O5-gate surface has been studied systematically by means
of field-effect and scanning electron microscopy methods. In
addition, the surface density of TMV particles loaded under
different incubation times has been investigated. Finally,
the field-effect sensor also demonstrates the label-free
detection of penicillinase immobilization as model
bioreceptor on TMV particles.},
cin = {IBI-3},
ddc = {620},
cid = {I:(DE-Juel1)IBI-3-20200312},
pnm = {5244 - Information Processing in Neuronal Networks
(POF4-524)},
pid = {G:(DE-HGF)POF4-5244},
typ = {PUB:(DE-HGF)16},
pubmed = {33418949},
UT = {WOS:000610520500001},
doi = {10.3390/mi12010057},
url = {https://juser.fz-juelich.de/record/904350},
}