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@ARTICLE{Oliveira:904356,
author = {Oliveira, Danilo A. and Molinnus, Denise and Beging, Stefan
and Siqueira, José R. and Schöning, Michael J.},
title = {{B}iosensor {B}ased on {S}elf‐{A}ssembled {F}ilms of
{G}raphene {O}xide and {P}olyaniline {U}sing a
{F}ield‐{E}ffect {D}evice {P}latform},
journal = {Physica status solidi / A},
volume = {218},
number = {13},
issn = {0031-8965},
address = {Weinheim},
publisher = {Wiley-VCH},
reportid = {FZJ-2021-05926},
pages = {2000747 -},
year = {2021},
abstract = {A new functionalization method to modify capacitive
electrolyte–insulator–semiconductor (EIS) structures
with nanofilms is presented. Layers of polyallylamine
hydrochloride (PAH) and graphene oxide (GO) with the
compound
polyaniline:poly(2-acrylamido-2-methyl-1-propanesulfonic
acid) (PANI:PAAMPSA) are deposited onto a p-Si/SiO2 chip
using the layer-by-layer technique (LbL). Two different
enzymes (urease and penicillinase) are separately
immobilized on top of a five-bilayer stack of the
PAH:GO/PANI:PAAMPSA-modified EIS chip, forming a biosensor
for detection of urea and penicillin, respectively.
Electrochemical characterization is performed by constant
capacitance (ConCap) measurements, and the film morphology
is characterized by atomic force microscopy (AFM) and
scanning electron microscopy (SEM). An increase in the
average sensitivity of the modified biosensors
(EIS–nanofilm–enzyme) of around $15\%$ is found in
relation to sensors, only carrying the enzyme but without
the nanofilm (EIS–enzyme). In this sense, the nanofilm
acts as a stable bioreceptor onto the EIS chip improving the
output signal in terms of sensitivity and stability.},
cin = {IBI-3},
ddc = {530},
cid = {I:(DE-Juel1)IBI-3-20200312},
pnm = {5241 - Molecular Information Processing in Cellular Systems
(POF4-524)},
pid = {G:(DE-HGF)POF4-5241},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000613842900001},
doi = {10.1002/pssa.202000747},
url = {https://juser.fz-juelich.de/record/904356},
}