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000904378 1001_ $$00000-0002-5234-0336$$aBloch, Carola$$b0$$eCorresponding author
000904378 245__ $$aAlexithymia traits outweigh autism traits in the explanation of depression in adults with autism
000904378 260__ $$a[London]$$bMacmillan Publishers Limited, part of Springer Nature$$c2021
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000904378 520__ $$aWhen contemplating the alarming depression rates in adults with autism spectrum disorder (ASD), there is a need to find factors explaining heightened symptoms of depression. Beyond the impact of autism traits, markedly increased levels of alexithymia traits should be considered as a candidate for explaining why individuals with ASD report higher levels of depressive symptoms. Here, we aim to identify the extent to which autism or alexithymia traits indicate depressive symptoms in ASD and whether the pattern of association are specific to ASD. Data of a large (N = 400) representative clinical population of adults referred to autism diagnostics have been investigated and split by cases with a confirmed ASD diagnosis (N = 281) and cases with a ruled out ASD diagnosis (N = 119). Dominance analysis revealed the alexithymia factor, difficulties in identifying feelings, as the strongest predictor for depressive symptomatology in ASD, outweighing autism traits and other alexithymia factors. This pattern of prediction was not specific to ASD and was shared by clinical controls from the referral population with a ruled out ASD diagnosis. Thus, the association of alexithymia traits with depression is not unique to ASD and may constitute a general psychopathological mechanism in clinical samples.
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000904378 7001_ $$0P:(DE-HGF)0$$aBurghof, Lana$$b1
000904378 7001_ $$0P:(DE-HGF)0$$aLehnhardt, Fritz-Georg$$b2
000904378 7001_ $$0P:(DE-Juel1)176404$$aVogeley, Kai$$b3$$ufzj
000904378 7001_ $$0P:(DE-HGF)0$$aFalter-Wagner, Christine$$b4
000904378 773__ $$0PERI:(DE-600)2615211-3$$a10.1038/s41598-021-81696-5$$gVol. 11, no. 1, p. 2258$$n1$$p2258$$tScientific reports$$v11$$x2045-2322$$y2021
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