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@ARTICLE{Bloch:904378,
      author       = {Bloch, Carola and Burghof, Lana and Lehnhardt, Fritz-Georg
                      and Vogeley, Kai and Falter-Wagner, Christine},
      title        = {{A}lexithymia traits outweigh autism traits in the
                      explanation of depression in adults with autism},
      journal      = {Scientific reports},
      volume       = {11},
      number       = {1},
      issn         = {2045-2322},
      address      = {[London]},
      publisher    = {Macmillan Publishers Limited, part of Springer Nature},
      reportid     = {FZJ-2021-05948},
      pages        = {2258},
      year         = {2021},
      abstract     = {When contemplating the alarming depression rates in adults
                      with autism spectrum disorder (ASD), there is a need to find
                      factors explaining heightened symptoms of depression. Beyond
                      the impact of autism traits, markedly increased levels of
                      alexithymia traits should be considered as a candidate for
                      explaining why individuals with ASD report higher levels of
                      depressive symptoms. Here, we aim to identify the extent to
                      which autism or alexithymia traits indicate depressive
                      symptoms in ASD and whether the pattern of association are
                      specific to ASD. Data of a large (N = 400)
                      representative clinical population of adults referred to
                      autism diagnostics have been investigated and split by cases
                      with a confirmed ASD diagnosis (N = 281) and cases with
                      a ruled out ASD diagnosis (N = 119). Dominance analysis
                      revealed the alexithymia factor, difficulties in identifying
                      feelings, as the strongest predictor for depressive
                      symptomatology in ASD, outweighing autism traits and other
                      alexithymia factors. This pattern of prediction was not
                      specific to ASD and was shared by clinical controls from the
                      referral population with a ruled out ASD diagnosis. Thus,
                      the association of alexithymia traits with depression is not
                      unique to ASD and may constitute a general
                      psychopathological mechanism in clinical samples.},
      cin          = {INM-3},
      ddc          = {600},
      cid          = {I:(DE-Juel1)INM-3-20090406},
      pnm          = {5251 - Multilevel Brain Organization and Variability
                      (POF4-525)},
      pid          = {G:(DE-HGF)POF4-5251},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:33500523},
      UT           = {WOS:000667511400012},
      doi          = {10.1038/s41598-021-81696-5},
      url          = {https://juser.fz-juelich.de/record/904378},
}