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@ARTICLE{Pais:904388,
      author       = {Pais, Patricia and Mateo, Celine and Pan, Wen-Ju and
                      Acland, Ben and Kleinfeld, David and Snyder, Lawrence H. and
                      Yu, Xin and Keilholz, Shella},
      title        = {{C}ontribution of animal models toward understanding
                      resting state functional connectivity},
      journal      = {NeuroImage},
      volume       = {245},
      issn         = {1053-8119},
      address      = {Orlando, Fla.},
      publisher    = {Academic Press},
      reportid     = {FZJ-2021-05958},
      pages        = {118630 -},
      year         = {2021},
      abstract     = {Functional connectivity, which reflects the spatial and
                      temporal organization of intrinsic activity throughout the
                      brain, is one of the most studied measures in human
                      neuroimaging research. The noninvasive acquisition of
                      resting state functional magnetic resonance imaging
                      (rs-fMRI) allows the characterization of features designated
                      as functional networks, functional connectivity gradients,
                      and time-varying activity patterns that provide insight into
                      the intrinsic functional organization of the brain and
                      potential alterations related to brain dysfunction.
                      Functional connectivity, hence, captures dimensions of the
                      brain's activity that have enormous potential for both
                      clinical and preclinical research. However, the mechanisms
                      underlying functional connectivity have yet to be fully
                      characterized, hindering interpretation of rs-fMRI studies.
                      As in other branches of neuroscience, the identification of
                      the neurophysiological processes that contribute to
                      functional connectivity largely depends on research
                      conducted on laboratory animals, which provide a platform
                      where specific, multi-dimensional investigations that
                      involve invasive measurements can be carried out. These
                      highly controlled experiments facilitate the interpretation
                      of the temporal correlations observed across the brain.
                      Indeed, information obtained from animal experimentation to
                      date is the basis for our current understanding of the
                      underlying basis for functional brain connectivity. This
                      review presents a compendium of some of the most critical
                      advances in the field based on the efforts made by the
                      animal neuroimaging community.},
      cin          = {INM-4},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-4-20090406},
      pnm          = {5253 - Neuroimaging (POF4-525)},
      pid          = {G:(DE-HGF)POF4-5253},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:34644593},
      UT           = {WOS:000714763700003},
      doi          = {10.1016/j.neuroimage.2021.118630},
      url          = {https://juser.fz-juelich.de/record/904388},
}