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@ARTICLE{DeBrito:904402,
      author       = {De Brito, Stephane A. and McDonald, Daniel and Camilleri,
                      Julia A. and Rogers, Jack C.},
      title        = {{C}ortical and subcortical gray matter volume in
                      psychopathy: {A} voxel-wise meta-analysis.},
      journal      = {Journal of abnormal psychology},
      volume       = {130},
      number       = {6},
      issn         = {0021-843x},
      address      = {Washington, DC},
      publisher    = {Assoc.},
      reportid     = {FZJ-2021-05972},
      pages        = {627 - 640},
      year         = {2021},
      abstract     = {Voxel-based morphometry (VBM) studies of gray matter volume
                      (GMV) in psychopathy have produced inconsistent results and
                      few have been replicated. Therefore, to clarify GMV
                      abnormalities associated with psychopathy as operationalized
                      by Hare (2003), we conducted a meta-analysis of VBM studies
                      using both categorical and dimensional analyses. We
                      identified seven studies eligible for the categorical
                      meta-analysis (136 men with psychopathy vs 150 male
                      controls) and 11 studies (N = 519) eligible for dimensional
                      metaregressions. First, we used seed-based d mapping with
                      permutation of subject images for voxel-based meta-analyses.
                      Statistical parametric maps of GMV were available for four
                      $(57\%)$ of the studies included in the categorical
                      meta-analysis and for five $(45\%)$ of the studies included
                      in the dimensional metaregression analyses, with peak
                      coordinates available for the remaining studies. Second, we
                      used metadata of a large-scale neuroimaging database to
                      provide an objective and quantitative account of
                      psychological processes attributed to the brain regions we
                      identified in our group meta-analysis and metaregressions.
                      Men with psychopathy exhibited reliable GMV abnormalities
                      circumscribed to the left hemisphere in the dorsolateral
                      prefrontal cortex and the medial orbitofrontal cortex. Total
                      psychopathy scores and Factors 1 and 2 scores were all
                      related to decreased GMV within those two prefrontal
                      regions, as well as decreased GMV in a wider set of regions
                      encompassing midline, temporal, parietal, occipital, and
                      subcortical structures. We discuss how decreased GMV in
                      those regions likely account for the impairments in the
                      emotion, cognition, action, and perception domains seen in
                      the disorder. (PsycInfo Database Record (c) 2021 APA, all
                      rights reserved)},
      cin          = {INM-7},
      ddc          = {150},
      cid          = {I:(DE-Juel1)INM-7-20090406},
      pnm          = {5254 - Neuroscientific Data Analytics and AI (POF4-525)},
      pid          = {G:(DE-HGF)POF4-5254},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:34553958},
      UT           = {WOS:000699925300006},
      doi          = {10.1037/abn0000698},
      url          = {https://juser.fz-juelich.de/record/904402},
}