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@ARTICLE{Lang:904834,
      author       = {Lang, Jessica and Stickel, Susanne and Gaum, Petra M. and
                      Habel, Ute and Bertram, Jens and Eickhoff, Simon B. and
                      Chechko, Natalia},
      title        = {{P}redicting {H}air {C}ortisol and {C}ortisone
                      {C}oncentration in {P}ostpartum {W}omen through {R}epeated
                      {M}easurements of {P}erceived {S}tress},
      journal      = {Metabolites},
      volume       = {11},
      number       = {12},
      issn         = {2218-1989},
      address      = {Basel},
      publisher    = {MDPI},
      reportid     = {FZJ-2022-00159},
      pages        = {815 -},
      year         = {2021},
      abstract     = {To investigate whether hair cortisol (HCC) and hair
                      cortisone (HCNC) can be predicted by repeated stress reports
                      from postpartum women in different mental health conditions
                      (non-depressed, ND, adjustment disorder, AD, postpartum
                      depression, PPD), 240 mothers (mean age 31.8 years; SD =
                      4.7) were monitored from within 1 to 6 days of childbirth
                      over a period of three months. HCC and HCNC in 3 cm hair
                      samples were assessed via triple mass spectrometry after
                      liquid chromatographic separation. Every second day,
                      participants reported their stress levels online. The summed
                      perceived stress scores were not found to be predictive of
                      HCC. However, perceived stress predicted a decrease in HCNC
                      (rSpearman = -0.153, p = 0.035) and an increase in the
                      HCC/HCNC ratio (rSpearman = 0.304, p < 0.001) in the ND
                      group. With AD in the first few weeks after childbirth, an
                      inverse effect appeared for HCNC (rSpearman = 0.318, p =
                      0.011), suggesting an overall downregulation of the HPA axis
                      owing to the stressful experience of adjusting to the new
                      situation. No effects were found for mothers developing PPD.
                      The indirect results of HPA-axis activity are better
                      indicators of the experience of psychological stress in
                      postpartum women than the absolute HCC value.},
      cin          = {INM-7},
      ddc          = {540},
      cid          = {I:(DE-Juel1)INM-7-20090406},
      pnm          = {5251 - Multilevel Brain Organization and Variability
                      (POF4-525)},
      pid          = {G:(DE-HGF)POF4-5251},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {34940573},
      UT           = {WOS:000735496000001},
      doi          = {10.3390/metabo11120815},
      url          = {https://juser.fz-juelich.de/record/904834},
}