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@ARTICLE{Tiso:904885,
      author       = {Tiso, Till and Winter, Benedikt and Wei, Ren and Hee,
                      Johann and de Witt, Jan and Wierckx, Nick and Quicker, Peter
                      and Bornscheuer, Uwe T. and Bardow, André and Nogales, Juan
                      and Blank, Lars M.},
      title        = {{T}he metabolic potential of plastics as biotechnological
                      carbon sources – {R}eview and targets for the future},
      journal      = {Metabolic engineering},
      volume       = {71},
      issn         = {1096-7176},
      address      = {Orlando, Fla.},
      publisher    = {Academic Press},
      reportid     = {FZJ-2022-00201},
      pages        = {77-98},
      year         = {2022},
      note         = {Biotechnologie 1},
      abstract     = {The plastic crisis requires drastic measures, especially
                      for the plastics’ end-of-life. Mixed plastic fractions are
                      currently difficult to recycle, but microbial metabolism
                      might open new pathways. With new technologies for
                      degradation of plastics to oligo- and monomers, these carbon
                      sources can be used in biotechnology for the upcycling of
                      plastic waste to valuable products, such as bioplastics and
                      biosurfactants. We briefly summarize well-known monomer
                      degradation pathways and computed their theoretical yields
                      for industrially interesting products. With this information
                      in hand, we calculated replacement scenarios of existing
                      fossil-based synthesis routes for the same products.
                      Thereby, we highlight fossil-based products for which
                      plastic monomers might be attractive alternative carbon
                      sources. Notably, not the highest yield of product on
                      substrate of the biochemical route, but rather the
                      (in-)efficiency of the petrochemical routes (i.e., carbon,
                      energy use) determines the potential of biochemical plastic
                      upcycling. Our results might serve as a guide for future
                      metabolic engineering efforts towards a sustainable plastic
                      economy.},
      cin          = {IBG-1},
      ddc          = {610},
      cid          = {I:(DE-Juel1)IBG-1-20101118},
      pnm          = {2172 - Utilization of renewable carbon and energy sources
                      and engineering of ecosystem functions (POF4-217)},
      pid          = {G:(DE-HGF)POF4-2172},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000793785100004},
      doi          = {10.1016/j.ymben.2021.12.006},
      url          = {https://juser.fz-juelich.de/record/904885},
}