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@ARTICLE{Steinkamp:906255,
author = {Steinkamp, Simon R. and Fink, Gereon R. and Vossel, Simone
and Weidner, Ralph},
title = {{S}imultaneous modeling of reaction times and brain
dynamics in a spatial cueing task},
journal = {Human brain mapping},
volume = {43},
number = {6},
issn = {1065-9471},
address = {New York, NY},
publisher = {Wiley-Liss},
reportid = {FZJ-2022-01326},
pages = {hbm.25758},
year = {2022},
abstract = {Understanding how brain activity translates into behavior
is a grand challenge in neuroscientific research.
Simultaneous computational modeling of both measures offers
to address this question. The extension of the dynamic
causal modeling (DCM) framework for blood oxygenation
level-dependent (BOLD) responses to behavior (bDCM)
constitutes such a modeling approach. However, only very few
studies have employed and evaluated bDCM, and its
application has been restricted to binary behavioral
responses, limiting more general statements about its
validity. This study used bDCM to model reaction times in a
spatial attention task, which involved two separate runs
with either horizontal or vertical stimulus configurations.
We recorded fMRI data and reaction times (n= 26) and
compared bDCM with classical DCM and a behavioral
Rescorla–Wagner model using Bayesian model selection and
goodness of fit statistics. Results indicate that bDCM
performed equally well as classical DCM when modeling BOLD
responses and as good as the Rescorla–Wagner model when
modeling reaction times. Although our data revealed
practical limitations of the current bDCM approach that
warrant further investigation, we conclude that bDCM
constitutes a promising method for investigating the link
between brain activity and behavior.},
cin = {INM-3},
ddc = {610},
cid = {I:(DE-Juel1)INM-3-20090406},
pnm = {5251 - Multilevel Brain Organization and Variability
(POF4-525)},
pid = {G:(DE-HGF)POF4-5251},
typ = {PUB:(DE-HGF)16},
pubmed = {34953009},
UT = {WOS:000733987000001},
doi = {10.1002/hbm.25758},
url = {https://juser.fz-juelich.de/record/906255},
}