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@ARTICLE{Pollok:906475,
      author       = {Pollok, Tania M. and Kaiser, Anna and Kraaijenvanger, Eline
                      J. and Monninger, Maximilian and Brandeis, Daniel and
                      Banaschewski, Tobias and Eickhoff, Simon B. and Holz,
                      Nathalie E.},
      title        = {{N}eurostructural traces of early life adversities: {A}
                      meta-analysis exploring age- and adversity-specific effects},
      journal      = {Neuroscience $\&$ biobehavioral reviews},
      volume       = {135},
      issn         = {0149-7634},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier Science},
      reportid     = {FZJ-2022-01478},
      pages        = {104589},
      year         = {2022},
      abstract     = {Early life adversities (ELAs) are associated with an
                      increased risk of psychopathology, with studies suggesting a
                      relation to structural brain alterations. Given the recently
                      growing evidence of ELA effects on brain structure, an
                      updated summary is highly warranted. Therefore, anatomical
                      likelihood estimation was used to conduct a coordinate-based
                      meta-analysis of gray matter volume (GMV) alterations
                      associated with ELAs, including sub-analyses for different
                      age groups and maltreatment as specific ELA-type. The
                      analyses uncovered a convergence of pooled ELA-effects on
                      GMV in the right hippocampus and amygdala and the left
                      inferior frontal gyrus, age-specific effects for the right
                      amygdala and hippocampus in children and adolescents, and
                      maltreatment-specific effects for the right perigenual
                      anterior cingulate cortex in adults. These results reveal a
                      possible underlying commonality in the impact of adversity
                      and also point to specific age and maltreatment effects.
                      They suggest neural markers of ELAs in regions involved in
                      socio-emotional functioning and stress regulation, with the
                      potential to be used as targets for interventions designed
                      to buffer or reverse harmful ELA-effects.},
      cin          = {INM-7},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-7-20090406},
      pnm          = {5252 - Brain Dysfunction and Plasticity (POF4-525)},
      pid          = {G:(DE-HGF)POF4-5252},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:35189164},
      UT           = {WOS:000819835100003},
      doi          = {10.1016/j.neubiorev.2022.104589},
      url          = {https://juser.fz-juelich.de/record/906475},
}