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@ARTICLE{Genon:907497,
      author       = {Genon, Sarah and Eickhoff, Simon B. and Kharabian,
                      Shahrzad},
      title        = {{L}inking interindividual variability in brain structure to
                      behaviour},
      journal      = {Nature reviews / Neuroscience},
      volume       = {23},
      number       = {5},
      issn         = {1471-003X},
      address      = {London},
      publisher    = {Nature Publ. Group},
      reportid     = {FZJ-2022-02056},
      pages        = {307 - 318},
      year         = {2022},
      abstract     = {What are the brain structural correlates of interindividual
                      differences in behaviour? More than a decade ago, advances
                      in structural MRI opened promising new avenues to address
                      this question. The initial wave of research then
                      progressively led to substantial conceptual and
                      methodological shifts, and a replication crisis unveiled the
                      limitations of traditional approaches, which involved
                      searching for associations between local measurements of
                      neuroanatomy and behavioural variables in small samples of
                      healthy individuals. Given these methodological issues and
                      growing scepticism regarding the idea of one-to-one mapping
                      of psychological constructs to brain regions, new
                      perspectives emerged. These not only embrace the
                      multivariate nature of brain structure-behaviour
                      relationships and promote generalizability but also embrace
                      the representation of the relationships between brain
                      structure and behavioural data by latent dimensions of
                      interindividual variability. Here, we examine the past and
                      present of the study of brain structure-behaviour
                      associations in healthy populations and address current
                      challenges and open questions for future investigations.},
      cin          = {INM-7},
      ddc          = {570},
      cid          = {I:(DE-Juel1)INM-7-20090406},
      pnm          = {5251 - Multilevel Brain Organization and Variability
                      (POF4-525)},
      pid          = {G:(DE-HGF)POF4-5251},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:35365814},
      UT           = {WOS:000777232500001},
      doi          = {10.1038/s41583-022-00584-7},
      url          = {https://juser.fz-juelich.de/record/907497},
}